Micro-sprinkling irrigation is a small-flow irrigation technology that uses the grouped outlets on the micro-sprinkling hoses to spray the pressure water evenly in the field. Plants' barriers during the middle to late growth period of winter wheat significantly reduce the irrigation quality of the micro-spray system. It is still unclear whether soil border width in wheat fields can alleviate the negative effect. In this study, a popularly-used variety (c.v. ZM 369) was adopted to test the mitigation effect of soil borders on irrigation quality, as well as soil moisture distribution, in wheat fields. Two irrigation quotas (i.e., 75 mm and 45 mm per time) and three border widths (i.e., 2.3 m, 3.3 m, and 5.3 m) were arranged in a randomized block design in the experimental years of 2020–2022. Soil moisture distribution and irrigation quality during the middle to late growth period of winter wheat (i.e., jointing to heading stage and grain filling stage) were investigated, as well as the effects on grain yield and water use efficiency (WUE). The results showed that irrigation water distribution in the direction perpendicular to micro-spray tapes generally decreased with the distance from tapes increasing. The maximum difference between the irrigation amount and water collected under the canopy was 134 mm. The uniformity coefficient of soil moisture distribution was increased by 25.8% with a 5.3 m border width compared to a 2.3 m width. Although an irrigation quota of 75 mm was beneficial for ensuring better irrigation uniformity and more stable grain yield, grain yield and WUE were produced with an irrigation quota of 45 mm. In conclusion, it is appropriate to increase border width and adopt a small quota for the micro-spray system in the North China Plain for wheat crops.