Dementia and cognitive impairment three months after stroke

Abstract

To investigate the cognitive capacities of a cohort of ischaemic or haemorrhagic stroke survivors and to identify the clinical determinants of post-stroke cognitive impairment, we evaluated 237 patients admitted to a Stroke Unit (mean age 59; SD=12.7). Three months after stroke, patients were submitted to a neuropsychological evaluation that included the Mini-Mental State Examination (MMSE), a complementary battery to assess specific cognitive domains, the Hamilton Depression Rating Scale (HDRS) and the Blessed Dementia Scale (BDS). Disturbed performance on at least one domain was detected on 131 (55%) patients: 27% had cognitive deficits other than memory, 7% had focal memory deficit, 9% had memory and other cognitive deficits and 6% had dementia. Dementia was associated with female gender (P=0.01), older age (P=0.01) and lower education level (P=0.04). Patients with memory deficits were older (P=0.01) with lower educational level (P=0.08) and more left sided lesions (P=0.02) than patients without memory deficits. In this middle aged stroke survivors cognitive impairment was common 3 months after stroke, while dementia was infrequent.

Depressão pós-AVC: aspectos psicológicos, neuropsicológicos, eixo HHA, correlato neuroanatômico e tratamento

“…Um grande estudo realizado com extensa bateria neuropsicológica encontrou 55% dos pacientes com comprometimento em pelo menos um domínio cognitivo, 27% com outros déficits cognitivos sem prejuízo da memória, 7% com déficits somente em memória e 9% com prejuízos em memória e outros déficits cognitivos 46 47 .…”

Endovascular middle cerebral artery occlusion in rats as a model for studying vascular dementia

“…Epidemiological studies have indicated that the prevalence of dementia in ischemic stroke patients is nine-fold higher than in controls 3 months after the stroke (Pohjasvaara et al 1998;Madureira et al 2001) and 4-12 times higher than in controls 4 years after a lacuna infarct (Loeb et al 1992). Even so, the prevalence of VaD may have been under-estimated, as the incidence of dementia varies considerably depending on which criteria are applied (Pohjasvaara et al 2000).…”

Arterielle Hypertonie und Demenz

“…Über die Konstruktion einer einfachen ätiopa-thogenetischen Reihe AH -Schlaganfall -vaskuläre Demenz (VD) ist die AH mit dem Syndrom Demenz verknüpft. Die Demenzinzidenz nach Schlaganfall wird in der Literatur mit 6-33% angegeben [52,59]. Für den Oberbegriff VD ist eine Reihe spezifischerer Unterteilungen vorgenommen worden.…”