Dementia and the risk of death in elderly patients with COVID‐19 infection: Systematic review and meta‐analysis

Zuin, Marco

doi:10.1002/gps.5468

Cited by 27 publications

(29 citation statements)

References 29 publications

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“…Hence, as new reviews continue to be published, the estimated numbers of individuals with COVID-19 and dementia might change. The strengths of our study were that it used updated literature regarding mortality among older adults with dementia who have COVID-19 and calculated the pooled odds ratio and pooled prevalence rates, making it of greater value compared to earlier published reports which only reported the prevalence of survival versus death in older adult with dementia who have COVID-19 39 , 40 , 41 .…”

Section: Discussionmentioning

confidence: 99%

Dementia as a mortality predictor among older adults with COVID-19: A systematic review and meta-analysis of observational study

Saragih

Saragih²,

Batubara

et al. 2021

Geriatric Nursing

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The purpose of this study was to systematically examine the association between dementia and mortality among older adults with COVID-19. To do so, we conducted a search of 7 databases for relevant full-text articles. A cohort study and case-control study were included. A meta-analysis was performed to synthesize the pooled odds ratio with a random-effects model. We identified studies that reported mortality among older adults with dementia and non-dementia who have COVID-19. The pooled mortality rates of dementia and non-dementia older adults infected with COVID-19 were 39% (95% CI: 0.23 – 0.54%, I 2 = 83.48%) and 20% (95% CI: 0.16 – 0.25%, I 2 = 83.48%), respectively. Overall, dementia was the main factor influencing poor health outcomes and high rates of mortality in older adults with COVID-19 infection (odds ratio 2.96; 95% CI 2.00 – 4.38, I 2 = 29.7%), respectively. Our results show that older adults with dementia with COVID-19 infection have a higher risk of mortality compared with older adults without dementia. This current study further highlights the need to provide focused care to the older adults with dementia or cognitive impairment who have COVID-19.

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Section: Discussionmentioning

confidence: 99%

Dementia as a mortality predictor among older adults with COVID-19: A systematic review and meta-analysis of observational study

Saragih

Saragih²,

Batubara

et al. 2021

Geriatric Nursing

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“…People with dementia are associated to a higher risk of death when infected with COVID‐19, 5 , 6 , 7 the caregivers encounter the dilemma between keeping the PwD at home to reduce the risk of infection and letting their beloved ones go out for necessary rehabilitation. The uncertainty about the development of the pandemic and the worry about what measures are to the best interest of the care recipients creates distress to caregivers.…”

Section: Introductionmentioning

confidence: 99%

The impact of dementia daycare service cessation due to COVID‐19 pandemic

Wong

Chui

Cheng

et al. 2021

Int J Geriat Psychiatry

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Objectives This study aimed at revealing the caregiving challenges of the caregivers of people with dementia (PwD) during the COVID‐19 pandemic when daycare service was stopped as an infection control measure, and discussed ways to help PwD and their family caregivers to maintain their well‐being in the era of the pandemic. Methods Between April and May 2020, a cross‐sectional survey was conducted in 152 family caregivers of PwD who were clients of daycare service prior to the pandemic. The survey examined caregivers' stress and challenges faced during daycare service cessation, their perceived needs for continuation of daycare service, and observed changes in functional status of PwD. Regression analyses were performed to explore the associated factors of caregiving stress and preference for continuation of daycare service. Results Family caregivers of PwD experienced greater caregiving stress after cessation of daycare service. Infection was their main challenge in caregiving, and their physical and emotional health was adversely affected by the longer time commitment with PwD under the stay‐home policy. Older age of caregivers, greater emotional and communication problems of PwD, and more time spent with PwD were associated with greater caregiving stress. More than one‐third of the participants preferred the continuation of daycare service during the pandemic. Conclusions Policy makers should consider the well‐being of PwD and their caregivers when planning infection control measures. Daycare service with enhanced infection controlled measures should remain available to PwD during the COVID‐19 pandemic.

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“…Older patients [ 26 , 27 ], living with dementia [ 28 ] or with multimorbid conditions, tend to have poor outcomes associated with COVID-19 infection. This cohort was more likely to reside in institutionalized care.…”

Section: Discussionmentioning

confidence: 99%

COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis

et al. 2021

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(1) Background: Older people with COVID-19 infection report worse clinical outcomes. There is a paucity of local data and this study aimed to describe the clinical progression of older people admitted to a university hospital in Malaysia with COVID-19 infection. (2) Methods: Older people (≥60 years) admitted with COVID-19 infection confirmed with RT-PCR from 27 February 2020–25 May 2020 were included in this study. Data on patient characteristics, hospital treatment, and inpatient outcomes were collected via hospital-held electronic medical records. Analysis was done to describe the cohort and identify factors associated with inpatient mortality. (3) Results: 26 participants were included (mean age 76.2 years, female 57.7%). All had at least one comorbid condition and half were frail. About 19.2% had non-respiratory (atypical) symptoms; 23.1% had a severe disease that required intensive care unit monitoring; 46.2% were given COVID-19 targeted therapy. Inpatient mortality and overall complication rates were 23.1% and 42.3%, respectively. Delirium on presentation and lower Ct-value were associated with mortality. (4) Conclusions: Older people with COVID-19 infection have severe infection and poor hospital outcomes. Vigilant hospital care is necessary to address their multimorbidity and frailty, along with appropriate treatment for their infection.

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Dementia and the risk of death in elderly patients with COVID‐19 infection: Systematic review and meta‐analysis

Cited by 27 publications

References 29 publications

Dementia as a mortality predictor among older adults with COVID-19: A systematic review and meta-analysis of observational study

Dementia as a mortality predictor among older adults with COVID-19: A systematic review and meta-analysis of observational study

The impact of dementia daycare service cessation due to COVID‐19 pandemic

COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis

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