Dementia, awareness and depression

Verhey, Frans R.J.; Rozendaal, Nico; Ponds, Rudolf; Jolles, J.

doi:10.1002/gps.930081008

Cited by 134 publications

(135 citation statements)

References 24 publications

Supporting

Mentioning

105

Contrasting

Unclassified

Order By: Relevance

“…It was anxiety that appeared related to awareness, with the low awareness group reporting significantly less anxiety than the moderate awareness group. This is consistent with the findings of the majority of previous studies [14,16,49], although some did not find this association [50]. Some studies have reported an association with self-reported quality of life in dementia [6], but others have found no such association [7].…”

Section: Discussionsupporting

confidence: 82%

“…The main methods of assessing awareness are general ratings of awareness based on interviews conducted by a clinician or researcher [16], calculation of discrepancies between patient and informant ratings on parallel questionnaires [17], and calculation of discrepancies between patient estimates of performance and actual task performance [18]. All have significant limitations [12,19,20].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Multidimensional Assessment of Awareness in Early-Stage Dementia: A Cluster Analytic Approach

Clare

Whitaker²,

Nelis³

et al. 2011

Dement Geriatr Cogn Disord

View full text Add to dashboard Cite

Background/Aims: Research on awareness in dementia has yielded variable and inconsistent associations between awareness and other factors. This study examined awareness using a multidimensional approach and applied cluster analytic techniques to identify associations between the level of awareness and other variables. Methods: Participants were 101 individuals with early-stage dementia (PwD) and their carers. Explicit awareness was assessed at 3 levels: performance monitoring in relation to memory, evaluative judgement in relation to memory, everyday activities and socio-emotional functioning, and metacognitive reflection in relation to the experience and impact of the condition. Implicit awareness was assessed with an emotional Stroop task. Results: Different measures of explicit awareness scores were related only to a limited extent. Cluster analysis yielded 3 groups with differing degrees of explicit awareness. These groups showed no differences in implicit awareness. Lower explicit awareness was associated with greater age, lower MMSE scores, poorer recall and naming scores, lower anxiety and greater carer stress. Conclusion: Multidimensional assessment offers a more robust approach to classifying PwD according to level of awareness and hence to examining correlates and predictors of awareness.

show abstract

Section: Discussionsupporting

confidence: 82%

Section: Introductionmentioning

confidence: 99%

Multidimensional Assessment of Awareness in Early-Stage Dementia: A Cluster Analytic Approach

Clare

Whitaker²,

Nelis³

et al. 2011

Dement Geriatr Cogn Disord

View full text Add to dashboard Cite

show abstract

“…The severity scores (range 1-3) of the observed individual neuropsychiatric symptoms were summed to generate a global score with a higher score for more severe behavioral symptoms. The degree of disease awareness was measured with the Guidelines for the Rating of Awareness Deficits (Verhey, Rozendaal, Ponds, & Jolles, 1993) in the Dutch cohort and according to the Reed anosognosia scale (Reed, Jagust, & Coulter, 1993) in the Nordic cohort. Both scales define awareness as the presence of explicit knowledge or recognition of own cognitive deficits according to a four-point scale.…”

Section: Independent Variablesmentioning

confidence: 99%

Determinants of quality of life in young onset dementia – results from a European multicenter assessment

Millenaar

Hvidsten

Vugt

et al. 2016

Aging & Mental Health

View full text Add to dashboard Cite

Background: Promoting adaptation, improving well-being and maintaining an optimal quality of life (QOL) is an important aspect in dementia care. The purpose of this study was to identify determinants of QOL in young onset dementia, and to assess differences in QoL domains between people with Alzheimer's disease (AD) and frontotemporal dementia (FTD). Methods: In total 135 persons with AD and 58 persons with FTD were included from two prospective cohort studies. QOL was assessed with the proxy reported quality of life in Alzheimer's disease questionnaire (QoL-AD). Possible determinants were explored using multiple linear regression and included sociodemographic variables, diagnosis, dementia severity, disease awareness, neuropsychiatric symptoms, met and unmet needs and hours of personal and instrumental care. Differences between QOL domains in people with AD and FTD were calculated using Mann-Whitney U tests. Results: Lower QOL was associated with more depressive symptoms, lower disease awareness, and a higher amount of needs, both met and unmet. People with AD scored lower on the memory and higher on the friends' subscale. No differences were found for the other items. Conclusion: This study demonstrates a unique set of determinants of QOL in AD and FTD. Interventions directed towards these specific factors may improve QOL.

show abstract

“…Direct assessment of individuals' awareness about their condition and its implications is usually made on the basis of an interview (Verhey, et al, 1993). However, this approach is not without problems, not least how to interpret the responses given.…”

mentioning

confidence: 99%

‘She might have what I have got’: The potential utility of vignettes as an indirect measure of awareness in early-stage dementia

Clare

Nelis

Martyr

et al. 2012

Aging & Mental Health

View full text Add to dashboard Cite

For the participants with dementia, awareness was assessed in separate in-depth interviews and rated on a 5-point scale for comparison purposes.Results: Participants with dementia were often able to correctly identify the problems described in the vignettes, although scoring lower than carers or controls. Participants with dementia were also able to offer advice for those depicted, although to a lesser extent than carers or controls. Ability to offer advice was greater where MMSE scores were higher. For participants with dementia, vignette scores were moderately correlated with ratings derived from interviews, and those showing limited or no awareness offered fewer items of advice than those showing some or good awareness. In addition, 29% of participants with dementia spontaneously pointed out similarities between their own condition and that of the person depicted.

show abstract

Dementia, awareness and depression

Cited by 134 publications

References 24 publications

Multidimensional Assessment of Awareness in Early-Stage Dementia: A Cluster Analytic Approach

Multidimensional Assessment of Awareness in Early-Stage Dementia: A Cluster Analytic Approach

Determinants of quality of life in young onset dementia – results from a European multicenter assessment

‘She might have what I have got’: The potential utility of vignettes as an indirect measure of awareness in early-stage dementia

Contact Info

Product

Resources

About