Demographic Characteristics of Seropositive Donors in Al-Khobar

Ankra-Badu, G.A.; Ahmad, Muhammad Bilal; Sowayan, Saleh; Bashawri, Layala

doi:10.5144/0256-4947.2001.113

Cited by 12 publications

(11 citation statements)

References 26 publications

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“…This was supported by an earlier study performed in eastern Saudi on blood donors from 1992 to 1998, in which statistically significant lower rates of anti‐HBc and anti‐HCV were seen among Saudis when compared with other nationalities, especially from developing countries (Ankra‐Badu et al. , 2001).…”

Section: Discussionsupporting

confidence: 64%

Prevalence of seromarkers of HBV and HCV among blood donors in eastern Saudi Arabia, 1998-2001

et al. 2004

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The prevalence of serological markers of HBV and HCV were determined for blood donors in eastern Saudi Arabia. Between 1998 and 2001, 13,443 donors (10,778 Saudi and 2665 non-Saudi), were screened for HBsAg, anti-HBc Ab, and anti-HCV Ab using commercial kits. There was a steady decrease in the HBsAg (2.58 and 1.67%), anti-HBc rates (15.32 and 9.15%), and anti-HCV (1.04 and 0.59%) rates between 1998 and 2001, respectively. However, there was a marked difference between Saudi and non-Saudi donors with regard to anti-HBc (P < 0.001) and anti-HCV (P < 0.01), but not HBsAg prevalence rates in the same time period.

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Section: Discussionsupporting

confidence: 64%

Prevalence of seromarkers of HBV and HCV among blood donors in eastern Saudi Arabia, 1998-2001

et al. 2004

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“…Also El-Hamzi (El-Hazmi 2004) showed that the percentage of non-Saudi donors declined from 17.2% at year 2000 to reach 14.8 by year 2002. Also Ankra-Badu et al (2001) previously showed that the proportion of Saudi blood donors increased with the decrease in the non-Saudis blood donors.…”

Section: Discussionmentioning

confidence: 86%

Hepatitis B and C Viruses incidence, the Risk Factors of Hepatocellular Carcinoma, is low in Aseer Region, Saudi Arabia

Alshehri

2013

Egyptian Academic Journal of Biological Sciences. C, Physiology

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Aim: Risks of hepatocellular carcinoma (HCC) following hepatitis B (HBV) and/or hepatitis C virus (HCV) infection are well known. The aim of this study was to determine the prevalence and risk factors of hepatitis B and C virus infections in blood donors at Aseer Region, Saudi Arabia Methods: The study was conducted on random blood samples collected from healthy blood donor volunteers, who were referred to Blood Transfusion Centers found at Aseer region, during the period March 2012 to February 2013. All the collected blood units were screened for hepatitis B surface antigen (HBsAg), anti-HBc, HCV, human immunodeficiency virus (HIV) 1 and 2, human T-cell lymphotropic virus (HTLV) I/II, venereal disease research laboratory (VDRL) and malaria. All donated blood were checked for HBV-DNA, HCV-RNA and HIV-RNA by nucleic acid test (NAT) technology. Results: Of 7267 (26 (0.36%) females and 7241 (99.64) males) blood donors screened, with median age of 28 (female) and 30 years (males), 71 (0.98%) were HBsAg positive of them 66 (0.91) were positive to HBV-DNA, 449 (6.18%) were anti-HBc positive of them 78 (1.07%) were positive to HBV-DNA. Cases positive to both HBsAg and HBc-Ab were 69 (0.95%) all of them were positive to HBV-DNA. There were 5 (0.069%) cases positive for HCV, none of them showed mixed infection with HVB. All positive cases for HBsAg, HBc-Ab and HCV were shown to be among male volunteers. Conclusion: Prevalence of HCV in Asser region is very low. In the time that HBsAg is low, prevalence of HBcAb is relatively moderate. Expected incidence of heptatocellular carcinoma due to infection with HCV is much lower than HBV.

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“…Occasionally, blood donor drives are conducted to obtain blood from security and educational institutions. Individuals who are required by law to donate blood before they are given a driver's license or national identity card (statutory donors) augment this pool (Ankra-Badu et al 2001). A volunteer donor pool has been found to be the safest source of blood worldwide (Eastlund 1998;Leikola 1998) and is endorsed by the WHO (1997).…”

Section: Introductionmentioning

confidence: 99%

“…A volunteer donor pool has been found to be the safest source of blood worldwide (Eastlund 1998;Leikola 1998) and is endorsed by the WHO (1997). In Saudi Arabia, anti-HCV test was introduced in 1994 and anti-HBc and anti-HTLV I/II tests were introduced in 1996 (Ankra- Badu et al 2001).…”

Section: Introductionmentioning

confidence: 99%

Hepatitis B Vaccine Reduced the Prevalence of Antibodies to Hepatitis B Core Antigen in Blood Donors in Aseer Region,Saudi Arabia

Ibrahim

Dajem

Heijan³

et al. 2014

Egyptian Academic Journal of Biological Sciences. C, Physiology

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Viral hepatitis is one of the major problem worldwide. The detection of hepatitis B virus (HBV) surface antigen (HBsAg), antibodies to HBV core antigen (HBc-Ab), and HBV-DNA in donated blood in Aseer Region (Southern part of Kingdom of Saudi Arabia) to detect prevention of the residual risk of transfusion transmitted HBV, donors in window period of HBV infection and the prevalence of HBV infection was attempted. The study was conducted on random blood samples collected from healthy blood donor volunteers, who were referred to blood transfusion centers found at Aseer region, during the period from March 2012 to January 2013. All the collected blood units were screened for hepatitis B surface antigen (HBsAg), anti-HBc, hepatitis C virus (HCV), human immunodeficiency virus (HIV) 1 and 2, human T-cell lymphotropic virus (HTLV) I/II, venereal disease research laboratory (VDRL), and malaria. All donated blood samples were checked for HBV-DNA, HCV-RNA, and HIV-RNA by nucleic acid test (NAT) technology. Of 6698 (19 females (0.28%) and 6679 males (99.72)) blood donors screened, with median age of 28 (female) and 30 years (males), 69 (1.03%) were HBsAg positive of them 64 (0.96) were positive to HBV-DNA, 411 (6.14%) were anti-HBc positive of them 73 (1.09%) were positive to HBV-DNA. Cases positive to both HBsAg and HBc-Ab were 68 (1.02%) of them 63 (0.94%) were positive to HBV-DNA. All HBsAg and HBc-Ab positive cases were shown to be among male volunteers. In conclusion, prevalence of HBsAg in Asser region is very low. The rate of HBc-Ab in units of blood donation is relatively high. The presence of HBV-DNA in HBc-Ab positive donations makes it risky for use. Vaccination program against HBV decreased the rate of HBV transmission.

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Demographic Characteristics of Seropositive Donors in Al-Khobar

Cited by 12 publications

References 26 publications

Prevalence of seromarkers of HBV and HCV among blood donors in eastern Saudi Arabia, 1998-2001

Prevalence of seromarkers of HBV and HCV among blood donors in eastern Saudi Arabia, 1998-2001

Hepatitis B and C Viruses incidence, the Risk Factors of Hepatocellular Carcinoma, is low in Aseer Region, Saudi Arabia

Hepatitis B Vaccine Reduced the Prevalence of Antibodies to Hepatitis B Core Antigen in Blood Donors in Aseer Region,Saudi Arabia

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