Demographic Correlates of Anxiety and Depression Symptoms in Chronic Sinonasal Diseases

Katotomichelakis, Michael; Simopoulos, Efthimios; Tzikos, Anthimos; Balatsouras, Dimitrios G.; Tripsianis, Gregory; Danielides, Gerasimos; Xenitidis, Kiriakos; Livaditis, Miltos; Danielides, Vassilios

doi:10.2190/pm.48.2.a

Cited by 27 publications

(23 citation statements)

References 22 publications

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“…However, as many of these were cohort studies, they may have been affected selection bias; also, they did not include non-referred subjects. Additionally, although AR and RS comorbidity is common [ 24 , 25 ], few studies considered the possibly synergistic effect of the condition on mental health and QoL [ 14 , 20 , 26 – 28 ]. Our present study is, to the best of our knowledge, the first population-based study to investigate mental health and the HRQoL of Koreans with AR and/or RS in consideration of a possible interaction between AR and RS.…”

Section: Discussionmentioning

confidence: 99%

Allergic rhinitis and rhinosinusitis synergistically compromise the mental health and health-related quality of life of Korean adults: A nationwide population-based survey

et al. 2018

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BackgroundAllergic rhinitis (AR) and rhinosinusitis (RS) negatively impact psychological well-being and health-related quality of life (HRQoL). However, few population-based studies have investigated the effects of these conditions on mental health and HRQoL.PurposeTo explore independent associations of AR and/or RS with mental health and HRQoL using data from the 2013–2015 Korea National Health and Nutrition Examination Survey (KNHANES).MethodsThe KNHANES is a nationwide cross-sectional survey of the non-institutionalized population of Korea. A total of 15,441 adults completed the clinical examination and the health questionnaire. We divided all participants into four groups: AR-/RS-, AR-/RS+, AR+/RS-, and AR+/RS+. Logistic regression analyses were performed after adjustment for sociodemographic characteristics, general health behaviors, and other comorbidities.ResultsThe AR+/RS+ group contained the highest proportion of subjects with perceived stress and depressed mood. Subjects with AR+/RS+ also had more frequent problems in terms of pain/discomfort and anxiety/depression. After adjusting for all confounders, the odds ratios (ORs) were 2.96 (p = 0.009) for depressed mood and 3.17 (p = 0.013) for suicidal ideation in the AR+/RS+ group compared with in the AR-/RS- group. The AR+/RS- group reported more perceived stress (OR, 1.56, p = 0.003) and depression (OR, 1.72, p = 0.024) compared with the AR-/RS- group. In terms of the ORs for HRQoL, the AR+/RS+ group reported more problems in terms of self-care (OR, 3.73, p = 0.038) and more pain/discomfort (OR 2.19, p = 0.006) compared with the AR-/RS- group.ConclusionsIn the Korean population, AR and RS exerted a synergistic negative impact on mental health and HRQoL, especially suicidal ideation. Most patients seek help from clinicians for impaired HRQoL. Therefore, clinicians should consider the underlying mental health and HRQoL of patients with AR and/or RS, as these may be impaired by their conditions.

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Section: Discussionmentioning

confidence: 99%

Allergic rhinitis and rhinosinusitis synergistically compromise the mental health and health-related quality of life of Korean adults: A nationwide population-based survey

et al. 2018

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“…Depression has been associated with anosmia, rhinitis, and chronic sinonasal disease in a number of studies. [35-38] While the exact cause is unknown, theories for the association include sleep disturbance, inflammatory cytokine upregulation, and common etiologic pathogenic factors. Depression and depressive syndromes have an extremely high prevalence among the elderly population, with rates ranging from 15 to 35%.…”

Section: Special Considerations In Older Adultsmentioning

confidence: 99%

Rhinitis in the Elderly

Baptist

Nyenhuis

2016

Immunology and Allergy Clinics of North America

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By the year 2050, the US aging population will nearly double. As the US aging population grows, it will be increasingly important for healthcare providers to effectively diagnose and manage rhinitis. The nasal symptoms of rhinorrhea, congestion, sneezing, nasal/ocular pruritus, and postnasal drainage affect up to 32% of older adults, and can significantly impact the quality of life. Several underlying factors associated with aging (such as structural changes and immunosenescence) may contribute to the pathogenesis of rhinitis in older adults. Although treatment options for rhinitis exist, special considerations need to be made as comorbidities, limited income, memory loss, and side effects of medications frequently occur in older adults and may impact outcomes.

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“…Many specifically only examined patients with chronic sinonasal disease or patients seeking medical attention for olfactory disorders. The relationship between major depression and changes in smell or taste has not been previously described in a nationally representative sample of U.S. adults . Even less is known about the relationship between gustatory disorders and depression; limited studies show an association between taste perception and affective disorders, and anecdotally clinicians have observed patients developing depression subsequent to gustatory dysfunction …”

Section: Introductionmentioning

confidence: 96%

“…The relationship between major depression and changes in smell or taste has not been previously described in a nationally representative sample of U.S. adults. 17,18 Even less is known about the relationship between gustatory disorders and depression; limited studies show an association between taste perception and affective disorders, and anecdotally clinicians have observed patients developing depression subsequent to gustatory dysfunction. 19,20 The National Health and Nutrition Examination Survey (NHANES) collected health surveys on taste and smell ability as well as related health conditions for the first time in representative samples in the U.S. in 2011-2012 and 2013-2014.…”

Section: Introductionmentioning

confidence: 99%

Association of alterations in smell and taste with depression in older adults

Hur

Choi

Zheng

et al. 2018

Laryngoscope Investig Oto

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ObjectiveExamine the relationship between depression and changes in smell or taste.Study DesignCross‐sectional analysis of 2011–2012 and 2013–2014 National Health and Nutrition Examination Survey (NHANES).MethodsWe examined 5,275 adults ≥40 years old who completed smell and taste questionnaires as well as a validated depression assessment instrument, the Patient Health Questionnaire (PHQ‐9). Analyses incorporated sampling weights to account for the complex sampling design and associations were analyzed using multivariate logistic regression adjusted for related demographics and socioeconomic data.ResultsThe prevalence of altered smell and taste was 23.0% (95% CI: 20.7–25.3%) and 11.9% (95% CI: 10.7–13.1%), respectively. Among those who met criteria for major depressive disorder, the prevalence of altered smell and taste was higher at 39.8% (95% CI: 33.4–46.1%) and 23.7% (95% CI: 18.7–28.7%), respectively. In a multivariate model adjusting for age, gender, education, major comorbidities, smoking history, heavy alcohol use, sinus disease, cold symptoms, and trauma history, adults ≥40 and <65 years old who reported alterations in smell (OR: 1.64, p = 0.004) and adults ≥40 years old who reported alterations in taste (OR: 1.77, p = 0.001) were more likely to meet criteria for major depressive disorder.ConclusionThere is a strong association between major depression and alterations in smell and taste among certain age groups in the general U.S. population. Primary care providers should screen for depression when patients report changes in smell or taste.Level of Evidence4.

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Demographic Correlates of Anxiety and Depression Symptoms in Chronic Sinonasal Diseases

Cited by 27 publications

References 22 publications

Allergic rhinitis and rhinosinusitis synergistically compromise the mental health and health-related quality of life of Korean adults: A nationwide population-based survey

Allergic rhinitis and rhinosinusitis synergistically compromise the mental health and health-related quality of life of Korean adults: A nationwide population-based survey

Rhinitis in the Elderly

Association of alterations in smell and taste with depression in older adults

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