Demographic expansions in South America: Enlightening a complex scenario with genetic and linguistic data

Ramallo, Virgínia; Bisso‐Machado, Rafael; Bravi, Cláudio M.; Coble, Michael D.; Salzano, Francisco M.; Hünemeier, Tábita; Bortolini, María Cátira

doi:10.1002/ajpa.22219

Cited by 39 publications

(39 citation statements)

References 56 publications

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“…Rapid genetic diversification has been an early hypothesis in genetic studies of South American populations (Neel 1973), and in more recent time may have been associated with the great linguistic diversity that is present today (Campbell 1997;Loukotka 1968;Ramallo et al 2013). The lack of substantial mitogenome data from Andean populations still leaves unresolved questions regarding any significant differentiation between east and west South America.…”

Section: Discussionmentioning

confidence: 99%

Identification of Whole Mitochondrial Genomes from Venezuela and Implications on Regional Phylogenies in South America

Lee¹,

Merriwether²

2015

Human Biology

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Recent studies have expanded and refined the founding haplogroups of the Americas using whole mitochondrial (mtDNA) genome analysis. In addition to pan-American lineages, a number of studies have identified specific variants that show higher frequencies in restricted geographical areas. In order to further characterize Native American maternal lineages and specifically examine local patterns within South America, we analyzed twelve maternally unrelated Yekuana whole mtDNA genomes from one village (Sharamaña) that include the four major Native American haplogroups A2, B2, C1, and D1. Our study proposes a reconfiguration of one subhaplogroup A2 (A2aa) that is specific to South America and identifies other singleton 2 branches across the four haplogroups. Furthermore, we show nucleotide diversity values that increase from north to south for haplogroups C1 and D1. The results from our work add to the growing mitogenomic data that highlight local phylogenies and support the rapid genetic differentiation of South American populations, which has been correlated with the linguistic diversity in the region by previous studies.3

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Section: Discussionmentioning

confidence: 99%

Identification of Whole Mitochondrial Genomes from Venezuela and Implications on Regional Phylogenies in South America

Lee¹,

Merriwether²

2015

Human Biology

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“…trajectories (Rothhammer and Dillehay, 2009;CallegariJacques et al, 2011;Amorim et al, 2013;Ramallo et al, 2013;Roewer et al, 2013;Sandoval et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

BetweenAndes andAmazon: The genetic profile of theArawak‐speakingYanesha

Barbieri

Heggarty

Yao

et al. 2014

American J Phys Anthropol

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The Yanesha are a Peruvian population who inhabit an environment transitional between the Andes and Amazonia. They present cultural traits characteristic of both regions, including in the language they speak: Yanesha belongs to the Arawak language family (which very likely originated in the Amazon/Orinoco lowlands), but has been strongly influenced by Quechua, the most widespread language family of the Andes. Given their location and cultural make-up, the Yanesha make for an ideal case study for investigating language and population dynamics across the Andes-Amazonia divide.In this study, we analyze data from high and mid-altitude Yanesha villages, both Y chromosome (17 STRs and 16 SNPs diagnostic for assigning haplogroups) and mtDNA data (control region sequences and 3 SNPs and one INDEL diagnostic for assigning haplogroups). We uncover sex-biased genetic trends that probably arose in different stages: first, a male-biased gene flow from Andean regions, genetically consistent with highland Quechua-speakers and probably dating back to Inca expansion; and second, traces of European contact consistent with Y chromosome lineages from Italy and Tyrol, in line with historically documented migrations. Most research in the history, archaeology and linguistics of South America has long been characterized by perceptions of a sharp divide between the Andes and Amazonia; our results serve as a clear case-study confirming demographic flows across that 'divide'. Am J Phys Anthropol 155:600-609,

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“…Cloning of pPCRs using L16070/H16259-L16234/H16422 and L16268/H16498 primers confirmed 100% and 99–100% of haplotype identification in SABMN00701 and SABMN704, respectively (S1 Fig). Haplogroup sequences for SABMN00701 and SABMN00704 revealed 100% and 99% identity, respectively, with haplogroup C1 from Native South Americans (KC676569 [49]; JQ996071 [50]; EU095227 [51]).…”

Section: Resultsmentioning

confidence: 99%

Tuberculosis in post-contact Native Americans of Brazil: Paleopathological and paleogenetic evidence from the Tenetehara-Guajajara

Guedes

Jaeger

Líryo³

et al. 2018

PLoS ONE

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Tuberculosis (TB) has been described in Native American populations prior to the arrival of European explorers, and in Brazilian populations dating from the Colonial Period. There are no studies demonstrating TB infection in native Brazilians, and the history and epidemiological scenario of TB in Brazil is still unknown. The aim of this study was to verify the presence of TB infection among the native Tenetehara-Guajajara population from Maranhão State, Brazil, 210 ± 40 years ago. A Tenetehara-Guajajara skeleton collection was submitted to paleopathological analysis, and rib bone samples (n = 17) were used for paleogenetic analysis based on Mycobacterium tuberculosis complex (MTC) targets. Porotic hyperostosis and cribra orbitalia were found in 10 and 13 individuals, respectively. Maternal ancestry analysis revealed Native American mtDNA haplogroups A and C1 in three individuals. Three samples showed osteological evidence suggestive of TB. katG and mtp40 sequences were detected in three individuals, indicating probable TB infection by two MTC lineages. Tuberculosis infection in the Tenetehara-Guajajara population since the 18th century points to a panorama of the disease resulting, most probably, from European contact. However, the important contribution of African slaves in the population of Maranhão State, could be also considered as a source of the disease. This study provides new data on TB during the Brazilian Colonial Period. This is the first report integrating paleopathological and paleogenetic data for the study of TB in Brazil.

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Demographic expansions in South America: Enlightening a complex scenario with genetic and linguistic data

Cited by 39 publications

References 56 publications

Identification of Whole Mitochondrial Genomes from Venezuela and Implications on Regional Phylogenies in South America

Identification of Whole Mitochondrial Genomes from Venezuela and Implications on Regional Phylogenies in South America

BetweenAndes andAmazon: The genetic profile of theArawak‐speakingYanesha

Tuberculosis in post-contact Native Americans of Brazil: Paleopathological and paleogenetic evidence from the Tenetehara-Guajajara

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