Demographic profile, clinical characteristics and outcomes of patients undergoing coronary artery bypass grafting—retrospective analysis of 4,024 patients

Varma, Praveen Kerala; Kundan, Simran; Ananthanarayanan, C; Panicker, Varghese Thomas; Pillai, Vivek; Sarma, P. Sankara; Karunakaran, Jayakumar

doi:10.1007/s12055-014-0318-5

Cited by 17 publications

(18 citation statements)

References 13 publications

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“…This was in agreement with Varma, et al [10], study in which the patients at the time of CABG surgery showed that hypertension was the commonest risk factors [10].…”

Section: Discussionsupporting

confidence: 90%

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Evaluation of the effect of coronary artery bypass grafting on the right ventricular function using speckle tracking echocardiography

Abdelmoneum¹,

Elmeligy²,

Eldarky³

et al. 2019

J Cardiol Cardiovasc Med

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Purpose: This was a prospective study conducted at Benha University hospital and National Heart Institute on one hundred patients undwent coronary artery bypass grafting (CABG) to evaluate the effect of CABG on the right ventricular (RV) function using speckle tracking echocardiography (STE). Methods: All cases were subjected to detailed medical history, full physical examination, 12 leads electrocardiogram (ECG), routine laboratory tests including (complete blood picture, liver functions, renal functions and lipid profi le) and echocardiography either conventional echocardiography or STE, all parameters obtained before and within 2 weeks after surgery. Results: By conventional echocardiography there was statistically signifi cant decrease in peak right ventricle systolic velociy (RVS´) from (12.76 ± 1.72) to (7.33 ± 1.71) and tricuspid annular plane systolic excursion (TAPSE) from (22.8 ± 3.99) to (13.77 ± 4.63) among the studied patients after CABG. While there was signifi cant increase in right ventricle fractional area change (RVFAC) from (44.69 ± 3.25) to (49.01 ± 3.36). On the other hand, there was non-signifi cant change in right ventricle end diastolic diameter (RVEDD) at mid-cavity from (26.37 ± 2.72) to (26.53 ± 2.72) and basal segment from (36.05 ± 2.98) to (36.29 ± 3.04), right ventricle stroke volume (RVSV) from (65.44 ± 7.02) to (65.85 ± 6.86) and right myocardial performance index (RMPI) from (0.491 ± 0.088) to (0.498 ± 0.086). Statistical analysis Data analysis was performed using the software SPSS (Statistical Package for the Social Sciences) version 20.

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“…This was in agreement with Varma, et al [10], study in which the patients at the time of CABG surgery showed that hypertension was the commonest risk factors [10].…”

Section: Discussionsupporting

confidence: 90%

“…A total of 4,024 patients performed CABG included in the study by Varma, et al [10], their mean age was 57 ± 9.6 years. The incidence of female patients undergoing surgery was the minority of cases (12.6%) [10].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the effect of coronary artery bypass grafting on the right ventricular function using speckle tracking echocardiography

Abdelmoneum¹,

Elmeligy²,

Eldarky³

et al. 2019

J Cardiol Cardiovasc Med

View full text Add to dashboard Cite

show abstract

“…When compared to the Western population, south Indian population who undergo CABG is usually younger and has high incidence of diabetes mellitus and ischemic cardiomyopathy. [24] The coronary arteries most often show diffuse involvement in diabetes mellitus. They are also smaller in size compared to Western population making CABG more technically challenging.…”

Section: Discussionmentioning

confidence: 99%

Female Gender is not a Risk Factor for Early Mortality after Coronary Artery Bypass Grafting

et al. 2019

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Background: The female gender is considered as a risk factor for morbidity and mortality after coronary artery bypass grafting (CABG). Aim: In this analysis, we assessed the impact of female gender on early outcome after CABG. Study Design: This is a retrospective analysis of data from our center situated in South India. Statistical Analysis: Patients were categorized according to gender and potential differences in pre-operative and post-operative factors were explored. Significant risk factors were then built in a multivariate model to account for differences in predicting gender influence on surgical outcome. Methods: 773 consecutive patients underwent first time CABG between January 2015 and December 2016. 96.77% of cases were performed using off-pump technique. 132 (17.07%) patients were females. These patients formed the study group. Results: The in-house/ 30-day mortality in females was similar to that of males (3.03% vs. 3.12%, p value 0.957). Mediastinitis developed more commonly in females (5.35% vs. 1.30%; p value 0.004) compared to males. There were more re-admissions to hospital for female patients (21.37% in females vs. 10.14% in males, p value <0.001). In multivariate analysis using logistic regression; there was a significant association between age (OR 1.08), chronic obstructive airway disease (OR 4.315), and use of therapeutic antibiotics (OR 6.299), IABP usage (OR 11.18) and renal failure requiring dialysis (OR 28.939) with mortality. Conclusions: Early mortality in females was similar to that of males. Females were associated with higher rate of wound infection and readmission to hospital.

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“…Over the past decade, a rapid increasing number of impaired LVEF or heart failure patients have undergone CABG. Chinese CABG Registry [ 17 ] and a survey from India [ 18 ] have reported that about 10% of all the CABG patients had LVEFs which were less than 50%. AKI affects 12–48% of patients undergoing CABG [ 6 ], it contributes to increased mortality and decreased quality of life [ 19 – 21 ], especially for those with heart failure or impaired LVEF.…”

Section: Discussionmentioning

confidence: 99%

A novel nomogram to predict perioperative acute kidney injury following isolated coronary artery bypass grafting surgery with impaired left ventricular ejection fraction

Lin

Hou

Tang

et al. 2020

BMC Cardiovasc Disord

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Background and objective Heart failure (HF) is a global health issue, and coronary artery bypass graft (CABG) is one of the most effective surgical treatments for HF with coronary artery disease. Unfortunately, the incidence of postoperative acute kidney injury (AKI) is high in HF patients following CABG, and there are few tools to predict AKI after CABG surgery for such patients. The aim of this study is to establish a nomogram to predict the incidence of AKI after CABG in patients with impaired left ventricular ejection fraction (LVEF). Methods From 2012 to 2017, Clinical information of 1208 consecutive patients who had LVEF< 50% and underwent isolated CABG was collected to establish a derivation cohort. A novel nomogram was developed using the logistic regression model to predict postoperative AKI among these patients. According to the same inclusion criteria and the same period, we extracted the data of patients from 6 other large cardiac centers in China (n = 540) from the China Heart Failure Surgery Registry (China-HFSR) database for external validation of the new model. The nomogram was compared with 3 other available models predicting renal failure after cardiac surgery in terms of calibration, discrimination and net benefit. Results In the derivation cohort (n = 1208), 90 (7.45%) patients were diagnosed with postoperative AKI. The nomogram included 7 independent risk factors: female, increased preoperative creatinine(> 2 mg/dL), LVEF< 35%, previous myocardial infarction (MI), hypertension, cardiopulmonary bypass(CPB) used and perioperative blood transfusion. The area under the receiver operating characteristic curve (AUC) was 0.738, higher than the other 3 models. By comparing calibration curves and decision curve analyses (DCA) with other models, the novel nomogram showed better calibration and greater net benefit. Among the 540 patients in the validation cohort, 104 (19.3%) had postoperative AKI, and the novel nomogram performed better with respect to calibration, discrimination and net benefit. Conclusions The novel nomogram is a reliable model to predict postoperative AKI following isolated CABG for patients with impaired LVEF.

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Demographic profile, clinical characteristics and outcomes of patients undergoing coronary artery bypass grafting—retrospective analysis of 4,024 patients

Cited by 17 publications

References 13 publications

Evaluation of the effect of coronary artery bypass grafting on the right ventricular function using speckle tracking echocardiography

Evaluation of the effect of coronary artery bypass grafting on the right ventricular function using speckle tracking echocardiography

Female Gender is not a Risk Factor for Early Mortality after Coronary Artery Bypass Grafting

A novel nomogram to predict perioperative acute kidney injury following isolated coronary artery bypass grafting surgery with impaired left ventricular ejection fraction

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