Demographics, clinical characteristics and management of herbicide poisoning in tertiary care hospital

Cherukuri, Harika; Pramoda, K.; Rohini, D.; Thunga, Girish; Vijaynarayana, K; Nair, Sreejayan; Varma, Muralidhar; Pandit, Vinay

doi:10.4103/0971-6580.139813

Cited by 37 publications

(39 citation statements)

References 27 publications

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“…The hospitalization time varied between 30 min to 1 day, with a mean hospitalization time of 4.25 days, which was similar to the findings of other studies. 3,10,11,13 The volume of Organo Phosphorus poison consumed was 60±55ml, which correlate with study done by Girish Thunga et al, 19 which showed volume of 48.9±52.5ml.…”

Section: Durationsupporting

confidence: 79%

The Profile of Organophosphorus Poisoning in Tertiary Care Hospital

Nagabhushana¹,

K²,

Ranganatha³

et al. 2015

jemds

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BACKGROUND:Organophosphates exposures are a global health problem especially in India. Although extensive data is available regarding the pattern of OP poisoning in India, there is only little information regarding the victim profiles and the factors which influence mortality in southern India. The present study aimed to analyze the patterns, the social factors and the clinical outcomes of OP poisoning in this region. MATERIAL AND METHODS: This study carried out in Medicine department, SIMS, Shimoga from July 1st, 2014 to Dec. 31st, 2014. A total of 74 cases of OP poisoning were studied. The diagnosis of the OP compound poisoning is done by history, examination and pseudo cholinesterase level estimation. RESULT: Out of a total of 74cases of poisoning, 33 (44.59%) were males and 41 (55.40 %) were females. Most of the cases were from the rural areas (45 cases-60.81%). Incidence is highest in illiterate (48.64%), the total percentage of the married cases was 67.56%, the highest number of cases (33.78%) was from the age group of 21 to 30 years. The OP poisoning occurred mainly during night (55.40%) highest in summer season (27 cases), the mean hospital stay was 4.25 days, with a majority of the cases staying for 3 to 7 days in the hospital (52.70%). The mortality in the present study was 29.72% (22 cases). The commonest OP compound poison consumed is chlorphyriphos. CONCLUSION: organ phosphorus poisoning is a major health hazard in the community. It needs to be managed rapidly with upgradation of treatment at PHC level. These findings demand a swing in emphasis in community education towards hazardous of the poisoning and design appropriate health education programme to reduce both mortality and morbidity.

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Section: Durationsupporting

confidence: 79%

The Profile of Organophosphorus Poisoning in Tertiary Care Hospital

Nagabhushana¹,

K²,

Ranganatha³

et al. 2015

jemds

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“…19 However, the finding was not in support with findings of other workers where majority of the patients were from rural areas the victims of OP poisoning mainly belonged to low class status 75 (96.15%). 12,13,20 This may be related to the fact that these individuals are more subjected to risk factors of stress like financial crisis, unemployment, domestic concerns thus increasing the incidence of poisoning.…”

Section: Discussionmentioning

confidence: 99%

Sociodemographic characSociodemographic characteristics and assessment of severity in organophosphorus poisoning in a tertiary care hospitalteristics and assessment of severity in Organophosphorous poisoning in a Tertiary care hospital

2017

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Background: In Nepal pesticide poisoning is a common problem and organophosphorus poisoning (OP) is the most common form of acute poisoning responsible for majority of deaths. However, sufficient data is still lacking from Western region of Nepal. The present study analysed the sociodemographic factors of OP poisoning cases, the association of severity based on admission clinical score (POP scale) and lag time with mortality.Methods: This is a cross-sectional study conducted in patients of organophosphorus poisoning, admitted to our casualty ward during a period of one-year June 2015 to 2016.Results: In this study incidence of OP poisoning was more in females 51 (65.38%) compared to males 27 (34.46%). The commonest age group involved in poisoning was 21-30 years 30 (38.4%). Housewives 32 (41.02%) were the commonest victims of poisoning. Incidence was high during rainy season 34 (43.58%) and mainly during late hours 27 (34.61%) of the day. Majority 24 (30.76%) cases reached hospital within 2 hours of poison intake. Methyl parathion (Metacid) 24 (30.76%) was the commonest OP compound consumed by the victims. Suicide 62 (79.48%) was the main motive of poison intake and financial problem (37.17%) was the main reason behind poison ingestion. In majority of the cases the sign and symptoms were mild (80.76%) in severity. In this study majority of the victims survived (9.30%) with prompt and appropriate treatment.Conclusions: The numbers of OP poisoning cases are increasing every year and poisoning is seen commonly in younger age groups. Therefore, strict legislature on the availability of OP compounds, preventive measures and appropriate health education should be introduced to decrease the incidence.

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“…Severity at HEMS contact does not appear to be different between the medical agents group and the other agents group, but it seems that if a pesticide is associated as the cause, mortality increases well over the medical agents group. Paraquat, in particular, had a high case fatality rate, and 45.5% of fatal cases reported in two previous studies were caused by paraquat 5, 6. Seven paraquat poisoning cases were transported by the Kanagawa HEMS, and only two of those survived.…”

Section: Discussionmentioning

confidence: 89%

Characteristic of the acute drug intoxication conveyed by Kanagawa helicopter emergency medical service

Sugita

Higami

Inoue

et al. 2017

Acute Medicine & Surgery

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AimVarious critical cases have been transported since the use of the Kanagawa Helicopter Emergency Medical Service (HEMS) started at Tokai University Hospital (Isehara, Japan) in 2002, including cases of acute poisoning. We analyzed the characteristics of acute poisoning cases conveyed by the HEMS.MethodsKanagawa HEMS conveyed 3,814 cases from July 2002 to March 2013, and acute drug and poison intoxication was diagnosed in 131 of these cases. We undertook a descriptive statistical study of these cases.ResultsThe causative agent was found to be psychiatric prescription drugs in 39.7% of cases, pesticides in 29.7%, alcohol in 8.4%, analgesics in 5.3%, detergent or bleach in 6.1%, oil, natural gas, or thinner in 4.6%, and others in 6.1%. At HEMS contact, systolic blood pressure was less than 90 mmHg in 18.3% of cases, and 40.2% were in coma. Endotracheal intubation was carried out in 44.5% of cases, and 6.9% died within 24 h of hospital admission. The cases of poisoning that we transported in the HEMS were often in shock and/or coma on arrival at the field, and rapid endotracheal intubation was required in nearly half of them, as many were in a serious condition.ConclusionWe believe that outcomes were more likely to be improved by appropriate early treatment by the HEMS. It will be necessary to further compare the ambulance service with the HEMS to evaluate their efficacy in the future.

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Demographics, clinical characteristics and management of herbicide poisoning in tertiary care hospital

Cited by 37 publications

References 27 publications

The Profile of Organophosphorus Poisoning in Tertiary Care Hospital

The Profile of Organophosphorus Poisoning in Tertiary Care Hospital

Sociodemographic characSociodemographic characteristics and assessment of severity in organophosphorus poisoning in a tertiary care hospitalteristics and assessment of severity in Organophosphorous poisoning in a Tertiary care hospital

Characteristic of the acute drug intoxication conveyed by Kanagawa helicopter emergency medical service

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