Demonstration of Noncontact Ultrasonic Mixing of Droplets

Nakamura, Ryohei; Mizuno, Yosuke; Nakamura, Kentaro

doi:10.7567/jjap.52.07he02

Cited by 29 publications

(23 citation statements)

References 31 publications

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“…22 In the recent years, different acoustic approaches have been proposed to manipulate liquid droplets. 14,[23][24][25][26][27][28] Koyama and Nakamura 23 developed a levitation system formed by a plane reflector and a metal plate attached to transducers at its ends. By changing the relative phase between the a) Author to whom correspondence should be addressed: marcobrizzotti@ gmail.com transducers, they could transport ethanol droplets.…”

Section: Introductionmentioning

confidence: 99%

Automatic contactless injection, transportation, merging, and ejection of droplets with a multifocal point acoustic levitator

Andrade

Camargo

Marzo

2018

Review of Scientific Instruments

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We present an acoustic levitation system that automatically injects, transports, merges and ejects liquid droplets in mid-air. The system consists of a phased array operating at 40 kHz on top of a plane reflector. The phase array generates multiple focal points at independent positions that form standing waves between the array and the reflector. In the reflector there is an inlet for a piezoelectric droplet injector which automatically inserts liquid droplets at the lower pressure nodes of the standing waves, and a hole that serves as an outlet for ejecting the processed droplets out of the system. Simulations of the acoustic radiation potential acting on the levitating droplets are in good agreement with the experiments. High-speed footage captured the functioning of the system in four fluidic operations: injection, transport, merging and ejection of liquid droplets. Having these operations integrated reliably into a single automatic system paves the way for the adoption of mid-air acoustophoretic processing in biological, chemical and pharmaceutical applications.

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Section: Introductionmentioning

confidence: 99%

Automatic contactless injection, transportation, merging, and ejection of droplets with a multifocal point acoustic levitator

Andrade

Camargo

Marzo

2018

Review of Scientific Instruments

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“…Turning to the research focused on droplet mixing only, there are numerous methods to mix droplets, such as a technique based on EWOD (Fowler, et al, 2002) and trapping droplets in the node of ultrasonic oscillation (Nakamura, et al, 2013). In these methods, droplets can be mixed with relatively simple operations such as switching the voltage to the appropriate electrode sequentially, or varying the amplitude of voltage in a cyclic manner.…”

Section: Received 3 July 2015mentioning

confidence: 99%

Biocompatibility of a droplet-mixing device using an electro-conjugate fluid

Takemura

Kobayashi

Edamura

2016

Mechanical Engineering Journal

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An electro-conjugate fluid (ECF) is a type of functional fluid that produces a jet flow under a non-uniform electric field. We use an ECF to generate a rotational flow in a tiny cylindrical chamber. When multiple droplets are dripped into the rotational flow of the ECF, they may be subjected to a centripetal force because of the difference in density between the droplets and ECF. This causes the droplets to move to the center of the chamber and mix with each other. In this paper, we conducted luminance measurements using a bioluminescence reaction to verify the suitability of this device for biological applications. We observed the luminescence produced by mixing droplets of luciferin and luciferase, and measured luminance maxima and area to assess the mixing ability of the device. In addition, because the enzyme luciferase can be deactivated by surroundings, we confirmed whether the proposed mixing method has any harmful influence on biological samples or not. To better understand the properties of the device, we conducted control experiments with two other set of conditions; i.e., without ECF and with still ECF. Our results confirmed that there was no difference in mixing ability between the three systems, and the influence of an electric-and centrifugal-field generated in the device on mixing might be negligible for biological applications.

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“…These uses depend on using powerful ultrasonic waves generated in air to induce physical actions. [1][2][3][4][5][6][7][8][9][10][11][12][13][14] Thus, a sound source for generating intense ultrasonic waves is required.…”

Section: Introductionmentioning

confidence: 99%

Aerial intense ultrasonic source integrating the horn and vibrating plate

Miura

2023

Jpn. J. Appl. Phys.

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The components of conventional high-intensity aerial ultrasonic sources, including the horn, longitudinal vibrating resonance bar, and transverse vibrating plates, are usually constructed separately. In this paper, a compact ultrasonic source that integrates all component parts was developed. First, the structure of the ultrasonic source was designed by simulation analysis with the finite element method. Next, an actual ultrasonic wave source was manufactured, and its electrical characteristics, vibration characteristics, and sound pressure distribution characteristics were measured. The ultrasonic source formed a strong standing wave sound field in the air, even though the total length was one wavelength of the longitudinal vibration. For an input electric power of 10 W, a high sound pressure in the standing wave sound field of 3.44 kPa was obtained (sound pressure level of about 165 dB).

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Demonstration of Noncontact Ultrasonic Mixing of Droplets

Cited by 29 publications

References 31 publications

Automatic contactless injection, transportation, merging, and ejection of droplets with a multifocal point acoustic levitator

Automatic contactless injection, transportation, merging, and ejection of droplets with a multifocal point acoustic levitator

Biocompatibility of a droplet-mixing device using an electro-conjugate fluid

Aerial intense ultrasonic source integrating the horn and vibrating plate

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