1953
DOI: 10.3181/00379727-83-20402
|View full text |Cite
|
Sign up to set email alerts
|

Demyelination in Lambs from Ewes which Feed on Seaweeds

Abstract: DEMYELINATIOK 11: LAMBS duced pain of the tooth pulp, by the method after the other 3 treatments. and discipline of Harris and Blockus. Rigorous elimination of bias was exercised. The treatments were: 4. d-amphetamine, 5 mg; amobarbital, 3 2 mg ; acetylsalicylic acid, 162 mg: acetophenetidin, 162 mg; B. acetylsalicylic acid, 162 mg; acetophenetidin, 162 mg: C. placebo; D. no medication. i.e., a dry-run. The threshold of experimentally induced pain was elevated more significantly during the 2% hours after the a… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

1957
1957
2020
2020

Publication Types

Select...
4
3

Relationship

0
7

Authors

Journals

citations
Cited by 13 publications
(2 citation statements)
references
References 0 publications
0
2
0
Order By: Relevance
“…To the knowledge of the present authors, copper deprivation has not been much studied in humans. In this context, it should be mentioned that, in a 60-year-old study of Icelandic ewes suffering from heavy copper shortage, the most conspicuous pathological defects in the brains of their lambs were lesions in neuronal myelin and demyelination 51,52. Whether lesions in the iron-rich myelin sheath as envisaged by Texel et al33 might contribute to the pathological distribution of iron in the AD brain is at present an open question.…”
Section: Resultsmentioning
confidence: 99%
“…To the knowledge of the present authors, copper deprivation has not been much studied in humans. In this context, it should be mentioned that, in a 60-year-old study of Icelandic ewes suffering from heavy copper shortage, the most conspicuous pathological defects in the brains of their lambs were lesions in neuronal myelin and demyelination 51,52. Whether lesions in the iron-rich myelin sheath as envisaged by Texel et al33 might contribute to the pathological distribution of iron in the AD brain is at present an open question.…”
Section: Resultsmentioning
confidence: 99%
“…as part of dairy-herd management, or to the greater vulnerability of young lambs to illness, predators, and physical trauma caused by falls while running (Baker and Britt, 1990;Hewson, 1984;Houston, 1977). Another possibility is nutrient deficiency: It has been observed that when nursing ewes consume seaweed, their lambs may develop a neurological disorder (so-called 'seaweed stagger') due to copper deficiency (caused by low Cu bioavailability in seaweed), which can lead to considerable lamb mortality (Hallsson, 1964;Ingimundarson, 1995;Palsson and Girmsson, 1953). Until the middle of the last century, the reason behind this disorder was not understood.…”
Section: Trophic Level Changesmentioning
confidence: 99%