The restriction of daily and economic-related activities due to COVID-19 pandemic via lockdown order has been reported to improve air quality. This study evaluated temporal and spatial variations of four major air pollutant concentrations across Malaysia before (March 4, 2020-March 17, 2020) and during the implementation of different phases of Movement Control Order (MCO) (March 18, 2020-May 12, 2020) from 65 official regulatory air quality stations. Results showed that restriction in daily and economic activities has remarkably reduced the air quality in all suburban , urban, and industrial settings with relatively small contributions from meteorological conditions. Overall, compared to before MCO, average concentrations of PM 2.5 , CO, and NO 2 reduced by 23.1%, 21.74%, and 54.0%, respectively, while that of SO 2 was constant. The highest reduction of PM 2.5 , CO, and NO 2 were observed in stations located in urban setting, where 63% stations showed significant reduction (p < 0.05) for PM 2.5 and CO, while all stations showed significant reduction in NO 2 concentrations. It was also revealed that 70.5% stations recorded lower concentrations of PM 2.5 during MCO compared to before MCO, despite that high numbers of local hotspots were observed simultaneously from NASA's Moderate Resolution Imaging Spectroradiometer (MODIS). Spatial analysis showed that the northern part of Peninsular had the highest significant reduction of PM 2.5 , while the highest of NO 2 and CO reduction were found in stations located in the central region. All pollutants exhibit similar diurnal trends when compared between pre-and during MCO although significant lower readings were observed during MCO. This study gives confidence to regulatory body; the enforcement of strict air pollution prevention and control policies could help in reducing pollution.