Demystifying Breast FNAC’s Based on the International Academy of Cytology, Yokohama Breast Cytopathology System- A Retrospective Study

Nargund, Ashwini; Mohan, Rakshitha Hosur; Pai, Malathi Mukunda; Sadasivan, Balu; Dharmalingam, Priya; Chennagiri, Premalata; Ramachandra, Chrishan J A

doi:10.7860/jcdr/2021/45366.14606

Cited by 4 publications

(8 citation statements)

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“…The ROM for this category was 16.6%. This was higher than the studies by Kamatar PV et al (0%) [9] , Appuroopa M et al (5%) [8] , Nargund A et al (7.69%) [7] , Wong S et al (2.6%) [5] and Montezuma D et al (4.8%) [4] . The study by Tejeswini V et al [10] had a higher ROM of 22.22% and Hoda RS et al [11] at 30.3% for this category.…”

Section: Discussionmentioning

confidence: 53%

“…The ROM here was 95.45%. This was higher than the studies of Wong S et al (84.6%) [5] , Kamatar PV et al (83%) [9] , Nargund A et al (83.3%) [7] , Appuroopa M et al (93.65%) [8] but slightly lower than studies of Wai CJ et al (97.1%) [6] and Tejeswini V et al (100%) [10] . Category 5 Malignant cytological diagnosis is given when there are definite cytological features.…”

Section: Discussionmentioning

confidence: 53%

“…In the remaining 7 cases 5 were diagnosed as invasive carcinoma and 2 of DCIS. The ROM of this category was 3.17% which was less than study of Tejeswini V et al (5.32%) [10] Nargund A et al (15.26%) [7] , Kamatar PV et al (4%) [9] , Hoda RS et al (4.7%) [11] but higher than studies of Appuroopa M et al (1.2%) [8] Montezuma D et al…”

Section: Discussionmentioning

confidence: 66%

“…The final aim of the system is to allow continuous improvement in breast cytology interpretation and thus helping the clinician managing the breast lesion [3] . The present study included FNAC samples of 649 female breast lesions making this a smaller study than those done by Montezuma D et al [4] Wong S et al [5] Wai CJ et al [6] Nargund A et al [7] Appuroopa M et al [8] but more cases than Kamatar PV et al [9] and Tejeswini V et al [10] The study by Montezuma D et al [4] was the first to categorize breast lesions by the new system and currently one of the largest studies done on the topic. In the present study histopathology diagnosis was available in 363 cases and these were used for statistical analysis.…”

Section: Discussionmentioning

confidence: 94%

“…(65.38%) [7] . The management of this category includes correlation with clinical and imaging findings along with repeat of FNAC.…”

Section: Discussionmentioning

confidence: 99%

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Breast FNA cytology reporting using new proposed IAC Yokohama reporting system: A single institution retrospective study

Joshee¹,

Joshee²

2021

Int. J. Adv. Res. Med.

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Introduction: Breast lumps are a common presenting complaint in general practice. Breast cancers are the most common cancers diagnosed over the world along with unfortunate rise in number of mortality due to them. Proper diagnostic evaluation is necessary. The fine needle aspiration cytology (FNAC) examination of breast lumps is important as it can be used either to differentiate between benign and malignant breast lesion or as an adjunct to core needle biopsy. In 2016 the IAC Yokohama five category reporting system was proposed to allow uniform reporting of breast FNA aspirates. Aim: The current study aims to reclassify breast lump aspirates using the proposed Yokohama reporting system and also to assess the risk of malignancy of each category. Materials and Methods: This single institution retrospective study included female breast lump FNAC cases over 4 year period. Clinical details of included cases were recorded from archives. Cytology slides were reevaluated as per new reporting system and the histopathology correlation was done where available. Statistical analysis was performed. Risk of malignancy of each category was calculated. Results: 649 breast FNAC cases were studied of average age 36.97 years. Maximum cases were in benign category followed by malignant category. Fibroadenoma was most common benign diagnosis. The risk of malignancy was 3.17% in benign category and 95.45% in suspicious for malignancy category. The diagnostic accuracy in current study was 97.83%. Conclusion: Use of a standard categorical cytology reporting system will give improved reports for better patient care.

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Section: Discussionmentioning

confidence: 53%

Section: Discussionmentioning

confidence: 53%

Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 94%

“…(65.38%) [7] . The management of this category includes correlation with clinical and imaging findings along with repeat of FNAC.…”

Section: Discussionmentioning

confidence: 99%

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Breast FNA cytology reporting using new proposed IAC Yokohama reporting system: A single institution retrospective study

Joshee¹,

Joshee²

2021

Int. J. Adv. Res. Med.

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Reporting breast fine needle aspiration cytology using the international academy of cytology Yokohama system: Experience in a tertiary care centre

Dhandapani,

Shankaralingappa,

Patel

et al. 2023

ACHR

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: In developing countries for all palpable breast lesions, Fine needle aspiration Biopsy (FNAB) is the most suitable test as FNAB is minimally invasive and cost-effective. The present study was undertaken to categorise the Breast Fine Needle Aspiration Biopsy (FNAB) samples according to the IAC Yokohama system of reporting and to assess the Risk of malignancy (ROM) for each category as well as to elucidate other quality indicators of the Breast FNAB. : Among the total 102 cases in which FNAC were performed, 9 were insufficient/ inadequate (8.80%), 11 were benign (10.80%), 5 were atypical (4.95%), 3 were suspicious (2.95%) and the rest 74 FNACs were malignant (72.5%). ROM of insufficient/inadequate, benign, atypical, suspicious and malignant ware 37.5%, 0%, 50%, 100% and 100% respectively. Absolute sensitivity (only category V) was 90.1 and complete sensitivity (including category III to V) was 96.3%. Specificity of IAC Yokohama system is 100% when considering category 5 as positive and is 88.9% when considering category 3 to 5 as positive. : The IAC Yokohama Reporting System for breast cytology has high sensitivity, specificity. The ROM in our study done in Indian population ware comparable to the proposed IAC Yokohama system which suggests the IAC Yokohama system has high reproducibility and can be applied in Indian population. Usage of FNAC for the evaluation of breast lumps and categorization based on the Yokohama system helps in ideal management of the patient, reducing the requirement of core needle biopsy.

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Utility of Yokohama system for classification of breast FNA

Nedunuri,

Swain

2024

IJPO

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Breast carcinoma is the most common malignancy among women globally. FNA is used as an important diagnostic tool as a part of triple assessment. The application of the IAC Yokohama system in breast cytology standardises reporting and also allows the calculation of risk of malignancy (ROM). To categorize all FNAC specimens according to the newly proposed IAC Yokohama reporting system for breast cytology. The ROM was determined for each category, sensitivity, specificity, negative and positive predictive values were evaluated to estimate the diagnostic accuracy of each category and inter-observer variability. 105 cases of breast FNACs were classified according to the IAC Yokohama system. The study was conducted over a period of 4 years and 9 months retrospectively from August 2018 to May2023. All FNACs were correlated with corresponding histology, but in most studies correlation of FNACs with histopathology was not possible in all cases because many were lost to follow-up. ROM for each category, Specificity, sensitivity, diagnostic accuracy, negative predictive value, positive predictive value and interobserver variability of FNAC were calculated. p-value was also calculated. Out of 105 breast FNACs, the category wise distribution from category 1 to 5, were category 1:4(3.8%), category2: 20(19.1%), category3: 16(15.2%), category4:5(4.8%) and category 5: 60(57.1%) respectively. The sensitivity, specificity, positive and negative predictive value and diagnostic accuracy was 90.3%, 100%, 100%, 82.5% and 93.3% respectively.: The Yokohama system has standardized, broadly used, and well-understood diagnostic categories, with clear criteria for inclusion in a category and appears to be reproducible by most cytopathologists.

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Demystifying Breast FNAC’s Based on the International Academy of Cytology, Yokohama Breast Cytopathology System- A Retrospective Study

Cited by 4 publications

References 0 publications

Breast FNA cytology reporting using new proposed IAC Yokohama reporting system: A single institution retrospective study

Breast FNA cytology reporting using new proposed IAC Yokohama reporting system: A single institution retrospective study

Reporting breast fine needle aspiration cytology using the international academy of cytology Yokohama system: Experience in a tertiary care centre

Utility of Yokohama system for classification of breast FNA

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