Reducing dose increases noise impacting image quality but can be offset by increasing display luminance. Two contrast detail mammography images were obtained at 26 kV and the same distance between detectors, at 45 and 50 mAs resulting in entrance surface doses of 7.09 and 7.88 mGy, respectively. They were processed to make average gray level of the background independent of the dose level while maintaining original SNR. Eight radiologists viewed the images at 420, , and SpotView™ a tool that resulted in an average display luminance of . Percent correct (PC) for all three luminances was higher for high versus low dose. Performance was always higher with high dose no matter what the luminance. For low dose, PC was highest with SpotView™, and SpotView™ and were significantly higher than . At high dose, SpotView™ PC was significantly higher than both lower luminances. Average time per image was lower in high dose, and, at both doses, time decreased as luminance increased, with SpotView™ having significantly shorter times. Increasing luminance from 420 to significantly increases target detection by and with SpotView™ by . Increasing display luminance with SpotView™ significantly decreases reading time by 16.0%.