Dendritic Architectures

Synthesis of Generational Polyester Dendrimers Derived from Glycerol and Succinic or Adipic Acid

“…Dendrimers are monodisperse macromolecules consisting of a central core from which branched repeat units extend outward in a fractal-like pattern. − As the molecular weight of the dendrimer increases, the structure in solution adopts a globular conformation. The degree to which a dendrimer attains this globular shape is determined by the solvent it is dissolved in, the multiplicities of the core and branches, the orientation of the branching functionalities, the flexibility of the branching units, and the length of the repeat unit. − The dendritic structure possesses three distinct regions which include the central core, branching units, and end groups.…”

In Situ Polymerized Hydrogels for Repairing Scleral Incisions Used in Pars Plana Vitrectomy Procedures

“…[1][2][3][4][5][6][7] To form such hydrogels, dendritic or highly branched macromers are advantageous. [8][9][10][11][12][13][14][15] These macromers provide opportunities to create hydrogels at low polymer concentration, to control swelling, and to vary the hydrogel mechanical properties. These favor-A C H T U N G T R E N N U N G able attributes arise with dendritic polymers because of the well-defined composition, the large number of endgroups, the physiochemical properties (such as low viscosity), and the preparation methods that allow for precise structural control and optimization capabilities.…”

Dendritic Macromers as in Situ Polymerizing Biomaterials for Securing Cataract Incisions

“…Dendritic macromolecules are versatile materials for medical applications since the chemical composition, structure, and molecular weight can be precisely controlled. − Moreover, the hyperbranched globular structure permits diverse and extensive surface functionalization, which facilitates subsequent intermolecular cross-linking, surface adhesion, or biological recognition. Cross-linkable dendritic macromolecules are known to form macroscopic gels, including hydrogels .…”