Dendritic Cells in Drug-induced Toxicity

Abstract

Dendritic cells play a key role in immunity and tolerance. They are the most abundant population of leukocytes in a number of different tissues and organs.

Interleukin-17 in Drug Toxicity

“…The immune system may either be protective or detrimental to the host. For example, in cisplatin-induced kidney injury, dendritic cells, T regulatory cells and IL-10 attenuate, whereas T cells, NK cells and IL-17 aggravate nephrotoxicity [1,2]. Recently, interleukin-17 research has gained much importance as a drug target for autoimmune and inflammatory diseases.…”