Dengue: A Neglected Disease of Concern

Abstract

BackgroundDengue fever, more prevalent in Asia, is a highly neglected vector-borne disease. It has a varied presentation ranging from common fever to atypical presentation as encephalitis. This study aimed to analyze the demographic and clinical profile of dengue patients admitted to a tertiary care center in Tamilnadu. MethodologyThis retrospective study was performed by collecting patient data from the medical records department for the years 2012 to 2014. A total of 150 patients with 50 patients from each year were selected. The patient's demographic data, clinical profile, management, and outcome were noted. Patients were divided into three groups as per the World Health Organization's 2009 classification. ResultsMost dengue cases occurred from October to December (70.7%). The number of male and female patients was almost equal (77 [51.3%] and 73 [48.7%], respectively). The middle-aged group (21-40 years) was commonly affected (54%). The mean age was 29 ± 13.20 years. Fever was the most common symptom (100%), followed by lethargy (81.3%) and myalgia (60.7%). Overall, 10% of patients had comorbidities such as diabetes, hypertension, and ischemic heart disease. Moreover, 22.7% of patients had dengue with warning signs, and severe dengue was seen in 19.3% of patients. A significant difference was noted in the total count, comorbidities, serositis, and the duration of hospitalization between the groups. No mortality was recorded in the study population. ConclusionsDengue is very common in the middle-aged group. Patients with severe dengue had significant leucopenia, several comorbidities, and serositis. The mortality can be reduced to <1% and even zero in severe dengue according to our study with close monitoring and supportive care.

Dengue Burden and Circulation of Dengue-2 Serotype Among Children Along With Clinical Profiling in Uttarakhand, India: A Cross-Sectional Study From 2018 to 2020

“…Bandyopadhyay et al also state that 11-20-year males were most affected age during the 2012 dengue outbreak in Kolkata [15]. Another study by Jisamerin et al demonstrates that fever was the primary symptom of DENV-positive patients, and most cases appeared from October to December in southern India [16]. One study modelled the role of anthropometric status on dengue in Colombian children in which DENV positivity was 60.8%.…”

Diabetes mellitus as a risk factor for severe dengue fever and West Nile fever: A meta-analysis

“…In total, 1700 studies were retrieved from the database in the initial search, of which 278 were considered potentially eligible after reviewing the titles and abstracts. After reading the full text of the articles, 31 articles were eligible, of which 4 studies used the same dataset as the others, and 27 articles were included in this meta-analysis [15,20,[25][26][27][28][29][30][31][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52]. The processes of study screening are shown in Fig 1, and the general characteristics of the included studies and the corresponding NOS scores are shown in Tables 1 and 2.…”