Dengue clinical features and harbingers of severity in the diabetic patient: A retrospective cohort study on Reunion island, 2019

Issop, Azizah; Bertolotti, A.; Diarra, Yves-Marie; Maïza, Jean-Christophe; Jarlet, Éric; Cogne, Muriel; Doussiet, E.; Magny, Éric; Maillard, Olivier; Nobécourt, Estelle; Gérardin, Patrick

doi:10.1016/j.tmaid.2023.102586

Cited by 2 publications

(1 citation statement)

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“…The study carried out by Luque 30 about clinical and epidemiological characteristics of dengue deaths in Piura during the FENC of 2017 found that the percentage of other diagnosis during admission in the first health establishment was notably less (16.7% versus 37.5%). A possible explanation for not suspecting dengue on behalf of clinicians could be the presence of nonconventional clinical patterns simulating other febrile diseases 29 , another possible explanation was the frequent association of dengue and advanced age and comorbidities which represent an added challenge for the diagnosis 33,34 . It is also possible that during the FENC 2023/Cyclone Yaku, the presentation of dengue cases had an unusual behavior, with a modified clinical presentation modified by circulating viral and bacterial coinfections (whose incidence increased with FENC and Cyclone Yaku) of which prior reports also exist [35][36][37] .…”

Section: Discussionmentioning

confidence: 99%

Time analysis of dengue deaths that occurred in two regions of Peru during the climatic-atmospheric phenomena El Niño Costero and Cyclone Yaku

Ramos,

Oyola-García,

Aguirre

et al. 2024

Preprint

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OBJECTIVE: To perform a dengue-related death time analysis that occurred in Piura and Ica (Peru) during the atmospheric phenomena of El Nino Costero and Cyclone Yaku in 2023. MATERIAL AND METHODS: A case-series study was performed. We included the deaths between January 1 and June 3, 2023. We reviewed the research data base of the deaths as well as the clinical epidemiology records, death certificates and laboratory test results. A time analysis was performed from the date of onset of symptoms, date of first visit at a health establishment, date that dengue diagnosis was first registered and date of death. RESULTS: We included 40 deaths by dengue in the study. 70% were females, the median age of death was 51 years of age, and 70% came from Piura. 51.2% presented some comorbidity and 14% had self-medicated with metamizole, other NSAIDS or corticoids before the initial medical consultation. 37.5% presented an unconventional clinical pattern at admission and dengue was not suspected in 40% during the initial assessment. The median time until the initial assessment, the diagnosis time, and the time from diagnosis until death were 3 days, 0 days, and 1 day, respectively. Adults presented a time until the initial assessment significantly greater than the other age groups (p=0.048), the diagnosis time was significantly less than those seen at the Health Department establishments and regional government establishments (MINSA/GORE) than in private establishments (p=0.014) and greater in pediatrics (p=0.018). The time from diagnosis until death was significantly less in those that self-medicated before the initial assessment (p=0.041). CONCLUSION: The adults presented a significantly greater time until the initial assessment; the diagnosis time was less than those seen in MINSA/GORE establishments and greater in pediatrics, furthermore, the time from diagnosis until death was significantly less in those who self-medicated before the initial assessment. An important fraction of deaths presented comorbidities and an unconventional clinical pattern at admission, with dengue frequently not suspected during the initial assessment.

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