Dengue fever related acalculous cholecystitis in a North Indian tertiary care hospital

Abstract

Acalculous cholecystitis should be strongly suspected in patients with dengue fever presenting with abdominal pain. Our study has shown that acalculous cholecystitis occurred in 14 out of 27 patients with dengue fever.

A case of acalculous cholecystitis in the course of dengue fever in a traveller returned from Brazil

“…The condition occurs in 7.6% to 38% of patients [9,21,22]. Typical symptoms include pain in the right hypochondriac region, fever, positive Murphy's sign, and abnormal liver function tests [6,9], which were observed in the presented case. A significant correlation between gallbladder wall thickening and the course of the disease (including progression to dengue haemorrhagic fever) has been demonstrated [6].…”

“…The thickening of gallbladder wall is the most frequent (43-59%) ultrasonographic finding in patients with dengue fever [15,16] whereas in the case of dengue haemorrhagic fever it may be found in up to 90% of patients [17][18][19][20]. The condition occurs in 7.6% to 38% of patients [9,21,22]. Typical symptoms include pain in the right hypochondriac region, fever, positive Murphy's sign, and abnormal liver function tests [6,9], which were observed in the presented case.…”

“…The acalculous cholecystitis has been described in the course of various diseases and conditions including trauma, vasculitis, parenteral alimentation, mechanical ventilation, salmonellosis, staphylococcal infections, brucellosis, leptospirosis, rickettsiosis or cytomegaly [6,[8][9][10][11][12][13][14]. The thickening of gallbladder wall is the most frequent (43-59%) ultrasonographic finding in patients with dengue fever [15,16] whereas in the case of dengue haemorrhagic fever it may be found in up to 90% of patients [17][18][19][20].…”

Acute Acalculus Cholecystitis in Dengue Hemorrhagic Fever-A Case Report

“…7 In another series of 27 dengue patients presenting with fever and abdominal pain in a Northern Indian tertiary care hospital, 17 were found to have acalculus cholecystitis. 8 Pathophysiology of acute acalculous cholecystitis is bile stasis due to gall bladder dyskinesia and ischemia which results in local inflammation in the gall bladder wall. In severe cases, necrosis of the gall bladder tissue and perforation occurs.…”

Surgical presentations with abdominal pain in dengue fever

“…Headache and abdominal pain are common manifestations. [1][2][3][4] Dengue fever is one of the commonest arbo-viral diseases around this part of the world with sudden insure in the number of cases observed during epidemics. In most of the cases it is asymptomatic, or presents with features common to any viral infection.…”