Dengue Hemorrhagic Encephalitis in Dengue Epidemic

Sheoran, Ankita; Singh, PrabhatKumar; Tetarwal, Pradeep; Singh, Pratap; Singh, Rajesh

doi:10.4103/jgid.jgid_147_22

Cited by 1 publication

(1 citation statement)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In encephalitis/encephalopathy cases, the use of high-dose steroids has been advocated in isolated case reports. 28 In addition, pulsed steroids may be helpful in ADEM, NMOSD and myelitis patients. Similarly, to other GBS causes, in DENV, intravenous immunoglobulin (IVIg) is also recommended.…”

Section: Denguementioning

confidence: 99%

Review of dengue, zika and chikungunya infections in nervous system in endemic areas

Puccioni-Sohler,

Nascimento Soares,

Christo

et al. 2023

Arq Neuropsiquiatr

View full text Add to dashboard Cite

Dengue, zika, and chikungunya are arboviruses of great epidemiological relevance worldwide. The emergence and re-emergence of viral infections transmitted by mosquitoes constitute a serious human public health problem. The neurological manifestations caused by these viruses have a high potential for death or sequelae. The complications that occur in the nervous system associated with arboviruses can be a challenge for diagnosis and treatment. In endemic areas, suspected cases should include acute encephalitis, myelitis, encephalomyelitis, polyradiculoneuritis, and/or other syndromes of the central or peripheral nervous system, in the absence of a known explanation. The confirmation diagnosis is based on viral (isolation or RT-PCR) or antigens detection in tissues, blood, cerebrospinal fluid, or other body fluids, increase in IgG antibody titers between paired serum samples, specific IgM antibody in cerebrospinal fluid and serological conversion to IgM between paired serum samples (non-reactive in the acute phase and reactive in the convalescent). The cerebrospinal fluid examination can demonstrate: 1. etiological agent; 2. inflammatory reaction or protein-cytological dissociation depending on the neurological condition; 3. specific IgM, 4. intrathecal synthesis of specific IgG (dengue and chikungunya); 5. exclusion of other infectious agents. The treatment of neurological complications aims to improve the symptoms, while the vaccine represents the great hope for the control and prevention of neuroinvasive arboviruses. This narrative review summarizes the updated epidemiology, general features, neuropathogenesis, and neurological manifestations associated with dengue, zika, and chikungunya infection.

show abstract

Section: Denguementioning

confidence: 99%