Dengue hemorrhagic fever complicated by pancreatitis

González-Fontal, Guido R.; Henao-Martínez, Andrés F

doi:10.1016/s1413-8670(11)70235-5

Cited by 12 publications

(10 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[22] The other unusual GI complications in the study were pancreatitis, cholecystitis, appendicitis, febrile diarrhea, and parotitis with very few cases reported in the past. [23242526]…”

Section: Discussionmentioning

confidence: 99%

Clinically profiling pediatric patients with dengue

Pothapregada

Kamalakannan

Thulasingham

et al. 2016

J Global Infect Dis

View full text Add to dashboard Cite

Objective:To study the clinical profile and outcome of dengue fever in children at a tertiary care hospital in Puducherry.Materials and Methods:All children (0-12 years of age) diagnosed and confirmed as dengue fever from August 2012 to January 2015 were reviewed retrospectively from hospital case records as per the revised World Health Organization guidelines for dengue fever. The diagnosis was confirmed by NS1 antigen-based ELISA test or dengue serology for IgM and IgG antibodies, and the data were analyzed using SPSS 16.0 statistical software. After collecting the data, all the variables were summarized by descriptive statistics.Results:Among the 261 confirmed cases of dengue fever non-severe and severe dengue infection was seen in 60.9% and 39.1%, respectively. The mean age (standard deviation) of the presentation was 6.9 + 3.3 years and male: female ratio was 1.2:1. The most common clinical manifestations were fever (94.6%), conjunctival congestion (89.6%), myalgia (81.9%), coryza (79.7%), headache (75.1%), palmar erythema (62.8%), and retro-orbital pain (51.3%). The common early warning signs at the time of admission were persistent vomiting (75.1%), liver enlargement (59.8%), cold and clammy extremities (45.2%), pain abdomen (31.0%), hypotension (29.5%), restlessness (26.4%), giddiness (23.0%), bleeding (19.9%), and oliguria (18.4%). The common manifestation of severe dengue infection was shock (39.1%), bleeding (19.9%), and multi-organ dysfunction (2.3%). The most common complications were liver dysfunction, acute respiratory distress syndrome, encephalopathy, pleural effusion, ascites, myocarditis, myositis, acute kidney injury, and disseminated intravascular coagulopathy. Platelet count did not always correlate well with the severity of bleeding. There were six deaths (2.3%) and out of them four presented with impaired consciousness (66.6%). The common causes for poor outcome were multiorgan failure, encephalopathy, and fluid refractory shock.Conclusion:There has been a resurgence of dengue fever with a change in the pattern of presentation during the recent epidemics. Clinical vigilance and awareness regarding the changing epidemic pattern and timely detection of cases are vital to reduce mortality and morbidity due to severe dengue infection.

show abstract

“…[22] The other unusual GI complications in the study were pancreatitis, cholecystitis, appendicitis, febrile diarrhea, and parotitis with very few cases reported in the past. [23242526]…”

Section: Discussionmentioning

confidence: 99%

Clinically profiling pediatric patients with dengue

Pothapregada

Kamalakannan

Thulasingham

et al. 2016

J Global Infect Dis

View full text Add to dashboard Cite

show abstract

“…Hyperlipasemia and enlarged pancreas have been known to occur in DF; but acute pancreatitis is an atypical and rare presentation. [6789] The largest described series was in an DHF outbreak in Taiwan in 2002 were pancreatitis (defined by a lipase level threefold greater than the upper limit of normal) was diagnosed in three patients with acute DHF, other few isolated cases have been described in Thailand, Indonesia, Noumea (New Caledonia), Colombia, India, and so on. [10] The exact pathogenesis of pancreatic involvement in dengue is not known.…”

Section: Discussionmentioning

confidence: 99%

Acute pancreatitis complicating severe dengue

Jain

Rao

et al. 2014

J Global Infect Dis

View full text Add to dashboard Cite

Dengue is an arthropod borne viral infection endemic in tropical and subtropical continent. Severe dengue is life threatening. Various atypical presentations of dengue have been documented. But we present a rare and fatal complication of severe dengue in form of acute pancreatitis. A 27-year-old male had presented with severe dengue in decompensated shock and with pain in abdomen due to pancreatitis. The pathogenesis of acute pancreatitis in dengue is not clearly understood, but various mechanisms are postulated. The awareness and timely recognition of this complication is very important for proper management.

show abstract

“…One series regarding DHF outbreak in Taiwan (2002) reported pancreatitis (defined by a lipase level 3-fold greater) in three patients with acute DHF and few other reports from other Asian countries [11]. Acute pancreatitis causing diabetes mellitus is a very rare manifestation of dengue [12]. The main clinical features of described 17 cases of pancreatitis in dengue infection are illustrated in Table 1.…”

Section: Discussionmentioning

confidence: 99%

“…Very few cases were reported dengue infection causing pancreatitis [12–14] and further leading to insulin requiring diabetes mellitus. This complication is under-reported and lack of awareness may prove fatal to a patient in DSS.…”

Section: Discussionmentioning

confidence: 99%

Dengue shock syndrome

Sudulagunta

Sodalagunta²,

Sepehrar

et al. 2016

Oxf Med Case Rep

View full text Add to dashboard Cite

Dengue fever is a mosquito-borne arthropod-borne viral (arboviral) tropical disease in humans affecting 50–528 million people worldwide. The acute abdominal complications of dengue fever are acute appendicitis, acute pancreatitis, acute acalculous cholecystitis and non-specific peritonitis. Acute pancreatitis with new onset diabetes in dengue shock syndrome (DSS) is very rarely reported. We describe a case of 30-year-old man admitted in intensive care unit and was diagnosed with DSS with RT-PCR, NS1 antigen and dengue IgM antibody being positive. Abdominal ultrasound and computerized tomography confirmed acute pancreatitis. Patient required insulin after recovery. Diabetes mellitus caused by DSS is under-reported and lack of awareness may increase mortality and morbidity.

show abstract

Dengue hemorrhagic fever complicated by pancreatitis

Abstract: Acute pancreatitis is an atypical complication of dengue fever and is rarely described. We are reporting a case of dengue hemorrhagic fever complicated by acute pancreatitis in a patient with history of diabetes mellitus type 1 and end stage renal disease on hemodialysis.

Cited by 12 publications

References 9 publications

Clinically profiling pediatric patients with dengue

Clinically profiling pediatric patients with dengue

Acute pancreatitis complicating severe dengue

Dengue shock syndrome

Contact Info

Product

Resources

About