Dengue Outbreak Management - Field Experience in Managing Dengue Involving an Urban Residential Area in Kota Kinabalu, Sabah Malaysia

Kaur, Narindeerjeet; Zakaria, Mohd Azimullah Abdullah; Rahim, Syed Sharizman Syed Abdul; Ibrahim, Mohd Yusof

doi:10.51200/bej.v2i1.3240

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…The number of death due to dengue also has increased from 16,957 in 1990 to 40,467 in 2017 [5]. Dengue fever outbreaks have already become epidemics causing high morbidity and mortality, as well as serious economic effects, particularly in South Asia and Southeast Asia [2], [6], [7], [8]. The World Health Organization (WHO) estimated there are 390 million cases per year with just 25% of the cases are symptomatic [3].…”

Section: Introductionmentioning

confidence: 99%

Wolbachia in Dengue Control: A Systematic Review

Nordin

Arsad

Mahmud

et al. 2022

Open Access Maced J Med Sci

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BACKGROUND: Dengue fever outbreaks have been an important public health issue causing high morbidity and mortality, and serious economic effects, particularly in Asia. Control strategies are a challenge to be implemented due to a variety of factors. However, new approaches such as Wolbachia-infected Aedes aegypti have been shown to successfully lowering the life spans of the mosquito, eggs resistance, and disease transmission capabilities. Field trials are still on-going, and there are data to support its benefit in a large population. This systematic review aims to determine the current progress and impact of using Wolbachia in curbing dengue cases in high dengue case locations worldwide. METHODOLOGY: The study uses the Preferred Reporting Items for Systematic reviews and Meta-Analyses review protocol, while the formulation of the research question was based on population of interest, comparison, and outcome. The selected databases include Web of Science, Scopus, PubMed, SAGE, and EBSCOhost. A thorough identification, screening, and included process were done and the results retrieved four articles. These articles were then ranked based on quality using mixed methods appraisal tool. RESULTS: A total of four articles were included from 2019 and 2020 reports in both dengue- and non-dengue-endemic settings. In this review, comparisons in terms of the hierarchy of the study design, community engagement and acceptance, Wolbachia-infected A. aegypti deployment, entomological outcome, and epidemiological outcomes were detailed. All four studies showed a decrease in dengue incidence in Wolbachia-intervention populations. CONCLUSION: Wolbachia programs have been shown to be an effective method in combating dengue diseases. Strong community engagement and involvement from multidisciplinary teams are important factors to ensure the effectiveness and good outcomes of the program.

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Section: Introductionmentioning

confidence: 99%

Wolbachia in Dengue Control: A Systematic Review

Nordin

Arsad

Mahmud

et al. 2022

Open Access Maced J Med Sci

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Evaluating the Predictive Ability of the Bipartite Dengue Contact Network Model

Labadin

Hong

Tiong

et al. 2022

2022 IEEE International Conference on Computing (ICOCO)

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E-dengue System Insights: Exploring the Factors Influencing Dengue-related Deaths in an Urbanized State in a Low-Middle Income Country (LMIC)

Abdul Rahman,

binti Wan Puteh,

bin Zainuddin

2024

BMC Public Health

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Background Dengue has emerged as a rapidly escalating health issue in low- and middle-income countries, with its burden and geographic spread increasing over the years. Malaysia, in particular, has witnessed a significant rise in dengue cases, accompanied by a spike in mortality rates. Several studies have identified various factors, primarily focusing on the 27 clinical aspects of severe dengue infection and the development of dengue-related fatalities. Expanding on this focus, this study aims to identify the demographic, clinical, and environmental factors contributing to dengue mortality, providing a more comprehensive understanding of the variables influencing dengue-related fatalities. Methods This study utilized a 1:2 case-control design, analyzing data from the E-dengue system database and medical records from January 2015 to December 2022, involving 219 participants (73 dengue fatalities as cases and 146 recovered patients as controls). Dengue deaths were confirmed by the Penang State Mortality Review Committee, and controls were randomly selected from laboratory-confirmed dengue cases. Statistical analyses were performed using SPSS software, including descriptive statistics, chi-square tests, and multivariable logistic regression to identify predictors of dengue mortality, with variables included in the multivariable model if p < 0.05. Results Several significant predictors of dengue-related mortality, including clinical and environmental factors were identified. Key predictors were a platelet count below 50,000/µL (OR 15.70; 95% CI: 5.65–43.53), presence of one comorbid condition (OR 2.90; 95% CI: 1.22–6.90), more than two comorbid conditions (OR 10.15; 95% CI: 3.53–29.23), bronchial asthma (OR 12.00; 95% CI: 1.08-132.13), and outbreak locality status (OR 2.3; 95% CI: 1.11–4.79). An interaction was also found between locality status and platelet levels. Conclusion The study emphasizes the need for developing risk profiles for dengue patients by integrating factors such as platelet levels, comorbidities, and locality status to improve clinical care. Nuanced protocols are needed to address the specific challenges of single-case and outbreak areas. In single-case localities, patients with low platelet counts (below 100,000/µL) should be prioritized for rapid intervention to mitigate severe outcomes. In outbreak areas, healthcare systems should bolster resources and apply comprehensive triage approaches considering platelet levels and other risk factors. Implementing predictive models that account for geographical factors can enhance resource allocation and preparedness for dengue outbreaks. These recommendations aim to empower public health personnel, healthcare providers, and communities to collectively reduce dengue-related mortality rates.

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Dengue Outbreak Management - Field Experience in Managing Dengue Involving an Urban Residential Area in Kota Kinabalu, Sabah Malaysia

Cited by 3 publications

References 19 publications

Wolbachia in Dengue Control: A Systematic Review

Wolbachia in Dengue Control: A Systematic Review

Evaluating the Predictive Ability of the Bipartite Dengue Contact Network Model

E-dengue System Insights: Exploring the Factors Influencing Dengue-related Deaths in an Urbanized State in a Low-Middle Income Country (LMIC)

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