2012
DOI: 10.1136/archdischild-2012-301710
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Dengue viral infection in children: a perspective

Abstract: Dengue is a vector-borne viral infection of global importance. Several pathogenetic mechanisms such as immune enhancement and selection pressure have been proposed and febrile, critical and recovery phases have been identified. A new classification proposed by WHO has recently been introduced where definitions have been changed to 'probable dengue', 'dengue with warning signs' and 'severe dengue'. The majority of dengue viral infections are self-limiting, but complications have high morbidity and mortality. Th… Show more

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Cited by 19 publications
(17 citation statements)
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References 35 publications
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“…Mortality is high among severe dengue. 17 In the present study, 2 children died due to severe dengue. As per WHO, 100 countries were found to be endemic for dengue.…”
Section: Discussionmentioning
confidence: 98%
“…Mortality is high among severe dengue. 17 In the present study, 2 children died due to severe dengue. As per WHO, 100 countries were found to be endemic for dengue.…”
Section: Discussionmentioning
confidence: 98%
“…In children, epistaxis, hepatomegaly and oliguria are more common 31. In older children and adults, headache, retro-orbital pain, arthralgia, petechiae and malaena are more common 31. Other symptoms may include diarrhoea, nausea, abdominal pain, cough and lymphadenopathy.…”
Section: Differential Diagnosismentioning
confidence: 99%
“…Children with a previous history of dengue infection are at increased risk of severe dengue. Dengue shock syndrome is more common than dengue haemorrhagic fever in children with severe dengue 31. Chikungunya has a similar presentation to dengue fever but typically with a more chronic polyarthralgia.…”
Section: Differential Diagnosismentioning
confidence: 99%
“…A identificação de sinais preditores de gravidade em dengue é uma das principais estratégias para reduzir a letalidade, particularmente em crianças, faixa etária em que a apresentação clínica é comumente inespecífica e com rápida evolução para o choque 1 .…”
Section: Introductionunclassified