2024
DOI: 10.3389/fimmu.2024.1260439
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Dengue virus exploits autophagy vesicles and secretory pathways to promote transmission by human dendritic cells

Alexandra P. M. Cloherty,
Anusca G. Rader,
Kharishma S. Patel
et al.

Abstract: Dengue virus (DENV), transmitted by infected mosquitoes, is a major public health concern, with approximately half the world’s population at risk for infection. Recent decades have increasing incidence of dengue-associated disease alongside growing frequency of outbreaks. Although promising progress has been made in anti-DENV immunizations, post-infection treatment remains limited to non-specific supportive treatments. Development of antiviral therapeutics is thus required to limit DENV dissemination in humans… Show more

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