“…Uddin et al (2012) also performed hematological analysis in beta-thalassemia patients in Bangladesh (16). Karim et al (2016) evaluated some of the essential trace element levels in beta-thalassemia major patients and controls, and reported that the serum iron value in these patients was close to the control values due to an oral iron chelating drug (17). Kumfu et al (2016) studied the effects of iron overload conditions on liver toxicity and hepcidin/ferroportin expression in thalassemic mice (18).…”