We study U (N ) k Chern-Simons theory coupled to fundamental fermions and scalars in a large N 't Hooft limit. We compute the thermal free energy at high temperature, as well as two-and three-point functions of simple gauge-invariant operators. Our findings support various dualities between Chern-Simons-matter theories with N = 0, 1, and 2 supersymmetry.1 When either N f or Ns = 0, i.e. when we have Chern-Simons theory coupled to purely scalar or fermion matter, there is evidence [36] for a different dual description slightly beyond the "flavor bounds." 2 Both sides of the proposed duality (1.1) are characterized by discrete data, the rank N , level k, and the number of fundamental fields, as well as an approximately marginal operator (ψφ)(φ † ψ). It is not known whether this operator becomes irrelevant or relevant at large but finite N .