Processing of the available experimental data on particles settling in shear-thinning polymer solutions is performed. Conclusions imply that sedimentation should be recursive, since settling also occurs within the sediment. To capture such an effect, a mathematical model of two continua has been developed, which corresponds to experimental data. The model is consistent with basic thermodynamics laws. The rheological component of this model is a correlation formula for gravitational mobility. This closure is justified by comparison with known experimental data available for particles settling in vertical vessels. In addition, the closure is validated by comparison with analytical solutions to the Kynch one-dimensional equation, which governs dynamics of particle concentration. An explanation is given for the Boycott effect and it is proven that sedimentation is enhanced in a 2D inclined vessel. In tilted vessels, the flow is essentially two-dimensional and the one-dimensional Kynch theory is not applicable; vortices play an important role in sedimentation.