Density Modification Methods

Podjarny, A.

doi:10.1007/978-1-4684-5272-3_5

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1991

2019

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“…The most popular of these approaches is the Wang (1985) procedure. This was successfully inserted into the general density-modification scheme (Podjarny, 1987) which was used from the beginnings of protein crystallography (see e.g. Qurashi, 1953).…”

Section: Introductionmentioning

confidence: 99%

Low-resolution phases: influence on SIR syntheses and retrieval with double-step filtration

Urzhumtsev¹

1991

Acta Cryst Sect A

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Different sources of error in single isomorphous replacement (SIR) maps are analysed. It is shown that SIR maps are good enough in themselves to localize a molecule but the absence of low-resolution reflections can distort the image of the molecule. Even in this case the molecule can be reliably localized using the double-step filtration technique of On the other hand, such syntheses may be considerably improved by addition of low-resolution structure factors. A very simple procedure is suggested to retrieve unknown phases for these structure factors.

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Section: Introductionmentioning

confidence: 99%