Dental anomalies in the primary dentition and their repetition in the permanent dentition: a diagnostic performance study

Abstract

This study investigated the recurrence in the permanent dentition of dental anomalies of the primary dentition. A sample of 189 subjects (100 males, 89 females, mean age of 5 years and 7 months) with anomalies of primary teeth (tooth hypodontia, supernumerary teeth, geminated teeth, and fused teeth) was selected and re-analyzed at a mean age of 11 years and 2 months for the recurrence of the dental anomalies in the permanent dentition. As a control group, 271 subjects (123 males, 148 females) without dental anomalies in the primary dentition were selected. The recurrence in the permanent dentition of the dental anomalies in the primary dentition was evaluated by measures of diagnostic performance. The results showed high values for the repetition of hypodontia (positive likelihood ratio = 102.0); low score for the repetition of hyperdontia (positive likelihood ratio = 6.5); low positive likelihood ratio (9.1) for gemination of primary teeth resulting in supernumerary permanent teeth; high positive likelihood ratio (47.0) for fusion of primary teeth followed by missing permanent teeth. Dental anomalies in the primary dentition are associated with an increased likelihood of anomalies of the succedaneous permanent.

Congenital Bilateral Missing Primary Mandibular Canines While Their Successors Exist- A Case Report

“…The likelihood ratio of eruption of permanent canines even though their primary predecessors are not erupted was found zero [12]. Higher values for the repetition of hypodontia and for fusion of primary teeth followed by missing permanent teeth were also demonstrated [12]. Acquired damage during early development has also some influence, suggesting multifactorial inheritance [1,12,13].…”

“…Hypodontia of primary teeth appears to be inherited in an autosomal dominant fashion, with incomplete penetrance and variable expressivity, whereas some cases present an autosomal recessive or sex-linked pattern [1,12,13]. The likelihood ratio of eruption of permanent canines even though their primary predecessors are not erupted was found zero [12].…”

“…It is widely accepted that if the primary tooth is missing, its succedaneous (permanent) tooth will also be missing [8][9][10][11]. Nevertheless, there are a few studies demonstrating a very rare possibility of existing permanent teeth in children who were missing the primary predecessors [12]. To our knowledge, no such case report is available.…”

Fusion with a supernumerary tooth: A case report

“…3 Marinelli ve ark. 7 ' nın yaptığı araştırmada, diş dizileri içinde incelenen 305 adet süt dişinden 34 tanesinde füzyon görülmüş, bunlardan 30 tanesinin sürekli diş dizileri içinde hipodontiye neden olduğu bildirilmiştir.…”

Prenatal Exposure to Antiepileptic Drugs and Dental Agenesis

“…Dental agenesis of the primary teeth is a rare condition and the estimated prevalence in Europe varies from 0.2–0.5% [12], [13]. Agenesis of primary teeth is almost always associated with agenesis of the equivalent permanent tooth [14], [15], but has to our knowledge never been associated with external harmful exposures.…”