Dental biofilm: Risks, diagnostics and management

Ray, Rina Rani

doi:10.1016/j.bcab.2022.102381

Cited by 8 publications

(6 citation statements)

References 56 publications

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“…Oral biofilm formation due to poor dental health lowers self-confidence and, in turn, gives rise to various psychological problems (Ray, 2022). Halitosis, a severe problem of bad oral smell, has an immense impact on psychological and social well-being.…”

Section: Psychosocial Problemsmentioning

confidence: 99%

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Oral biofilm: Systemic and psychiatric implications

Ray,

Pattnaik

2023

SEHS

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The oral cavity, being an excellent residence for a plethora of microbes, forms biofilm in various compartments. Acting as a preferable habitat with rich nutrients and other facilities, it hosts an array of bacteria, along with members of fungi, archaea, protozoa, and viruses that naturally or accidentally reside in the oral cavity. The dysbiosis of oral microbiota induces diseases and disorders in various physiological systems, including cardiovascular, respiratory, digestive, excretory, reproductive, immune, and neurological systems, leading to various diseases and even cancer. Neurological and other disorders contribute to several psychiatric ailments. Hence, oral ill health not only leads to diseases such as periodontitis and tooth loss but might also result in unpredictable diseases, including carcinogenesis. Oral problems also lead to cognitive dysfunction, dementia, and other psychosocial embarrassments. The induction of these deadly diseases might be predicted by analyzing the oral microbial composition; therefore, the overabundance of microbes such as Porphyromonas gingivalis and Fusobacterium in the oral microbiome might be used as the bioindicator of various diseases, proving the unequivocal role of oral biofilm in the onset of various systemic and psychiatric ailments.

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Section: Psychosocial Problemsmentioning

confidence: 99%

“…The favorable conditions of temperature, pH, nutrient supply, and other factors facilitate their flourishing. The composition of the biofilm, along with its relationship with the host, plays a key role in maintaining good oral health (Samaranayake and Matsubara, 2017). The dysbiosis of this equilibrium marks the collapse of overall health.…”

Section: Introductionmentioning

confidence: 99%

Oral biofilm: Systemic and psychiatric implications

Ray,

Pattnaik

2023

SEHS

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“…More than 3.5 billion people are affected by oral disorders, which significantly lower the quality of life, particularly in many low- and middle-income nations [ 1 , 5 , 6 , 7 , 8 , 9 ]. Dental plaque has been recognized as a biofilm in recent years [ 10 ]. Oral biofilm is the three-dimensional arrangement of various microorganisms residing in the mouth cavity.…”

Section: Introductionmentioning

confidence: 99%

“…Human tooth decay and the inflammatory degeneration of the alveolar bone are caused by oral biofilms [ 11 ]. If the biofilm remains untreated, it can undergo maturation, leading to the development of dental caries [ 10 ]. Dental caries is a long-lasting disease that leads to the demineralization of enamel, dentin, and cementum.…”

Section: Introductionmentioning

confidence: 99%

“…Bacterial biofilms are observed on oral mucous membranes, tooth surfaces, and dental prosthetic items in regions connected to oral health care. The causative agent in dental caries and periodontal illnesses is a biofilm, which manifests as supragingival and subgingival plaque [ 10 ]. Oral biofilms are multispecies microbial colonies that show strong antibiotic resistance [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

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Application of Three Compounds Extracted from Cynodon dactylon against Streptococcus mutans Biofilm Formation to Prevent Oral Diseases

Habib,

Rahman,

Nair

et al. 2023

Biomolecules

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Streptococcus mutans bacteria form a biofilm called plaque that causes oral diseases, including tooth decay. Therefore, inhibition of biofilm formation is essential to maintaining good oral health. The health and nutritional benefits of Cynodon dactylon are well documented, but very little is known about its use to treat against oral diseases. The aim of this study was to detect the adhesion strength of the S. mutans bacterial biofilm in 100 cases in the Rajshahi region and evaluate the inhibitory activity of different compound extracts of C. dactylon on the S. mutans bacterial biofilm by determining the composition of isolated compounds using phytochemical analysis. Nuclear magnetic resonance (NMR) spectroscopy confirmed that three specific compounds from C. dactylon were discovered in this study: 3,7,11,15 tetramethyl hexadec-2-4dien 1-o1, compound 3,7,11,15 tetramethylhexadec-2-en-1-o1 from phytol derivatives, and stigmasterol. Results indicated that the compound of 3,7,11,15-tetramethyl-hexadec-2-en-1-ol exhibited higher antibiofilm activities on S. mutans than those of the other compound extracts. A lower level of minimum inhibitory concentration was exposed by 3, 7, 11,15 tetramethyl hexadeca-2-en-1-o1 (T2) on S. mutans at 12.5 mL. In this case, the compound of 3,7,11,15 tetramethyl hexadec 2en-1-o1 was used, and patients showed a mean value and standard error reduced from 3.42 ± 0.21 to 0.33 ± 0.06 nm. The maximum inhibition was (80.10%) in the case of patient no. 17, with a value of p < 0.05 found for S. mutans to which 12.5 μL/mL ethyl acetate extract was applied. From these findings, it may be concluded that C. dactylon extracts can be incorporated into various oral preparations to prevent tooth decay.

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