2014
DOI: 10.1016/j.joms.2014.06.443
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Dental Extraction in the Neutropenic Patient

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Cited by 15 publications
(16 citation statements)
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“…Nevertheless, impaired wound healing has been described as a clinical feature of congenital neutrophil disorders in humans (146,147). Case reports also showed wound healing improvements in neutropenic patients receiving G-CSF (148,149), and in one study assessing dental extraction in neutropenic patients, delayed wound healing was the most prevalent complication (150). As such, the limited human data do support a role for neutrophils as players in wound healing and warrant attention in the development of strategies to improve wound repair.…”
Section: Discussionmentioning
confidence: 99%
“…Nevertheless, impaired wound healing has been described as a clinical feature of congenital neutrophil disorders in humans (146,147). Case reports also showed wound healing improvements in neutropenic patients receiving G-CSF (148,149), and in one study assessing dental extraction in neutropenic patients, delayed wound healing was the most prevalent complication (150). As such, the limited human data do support a role for neutrophils as players in wound healing and warrant attention in the development of strategies to improve wound repair.…”
Section: Discussionmentioning
confidence: 99%
“…As cirurgias orais menores podem ser realizadas com segurança em indivíduos com contagem de plaquetas ≥30.000/µL (28) com possibilidade de intervenções cirúrgicas em contagem de plaquetas igual a 20.000/µL (29) . Os indivíduos que estão classificados nos grupos de risco baixo ou moderado para a ocorrência de hemorragia (quadro 1) podem ser manejados por meio de adequada sutura associada ou não a agentes hemostáticos locais, como por exemplo: celulose oxidada (Surgicel®, Ethicon, Somerville, NJ; ActCel Coreva, Westlake Village, CA), espumas de gelatina (Gelfoam®, Pfizer, New York, NY; Surgifoam®, Ethicon, Somerville, NJ), ostene (Ceremed Inc., Los Angeles, CA), colágeno microfibrilar (Avitene Davol, Warwick, Reino Unido; Instat Ethicon 360, Somerville, NJ), ácido tânico, ácido epsilonaminocapróico, ácido tranexâmico e cola de fibrina desde que não haja infecção local instalada.…”
Section: C) Cuidados Pré Trans E Pós-cirúrgicosunclassified
“…Como opções terapêuticas em relação ao manejo pré-operatório dos indivíduos que evoluem com neutropenia, podemos citar o uso de alguns antimicrobianos: meropenem, cefazolina, clindamicina, cefepime, ampicilina com sulbactam e a vancomicina (29) . No entanto, não existe clareza na literatura sobre a escolha do medicamento ou da melhor indicação quanto o uso profilático ou terapêutico.…”
Section: C) Cuidados Pré Trans E Pós-cirúrgicosunclassified
“…Oral and dental infections might complicate the cancer treatment and lead to morbidity and an inferior quality of life for pediatric cancer patients [1,[11][12][13]. Early detection and radical therapy reduce the risk of oral infection and its associated systemic complications.…”
Section: Introductionmentioning
confidence: 99%