Dental implants in irradiated versus nonirradiated patients: A meta‐analysis

Abstract

The purpose of the present meta-analysis was to test the null hypothesis of no difference in dental implant failure rates, postoperative infection, and marginal bone loss for patients being rehabilitated by dental implants and being previously irradiated in the head and neck region versus nonirradiated patients against the alternative hypothesis of a difference. The study suggests that irradiation negatively affects the survival of implants, as well as the difference in implant location (maxilla vs mandible), but there is no statistically significant difference in survival when implants are inserted before or after 12 months after radiotherapy. The study failed to support the effectiveness of hyperbaric oxygen therapy in irradiated patients. It was observed that there was a tendency of lower survival rates of implants inserted in the patients submitted to higher irradiation doses. The results should be interpreted with caution because of the presence of uncontrolled confounding factors in the included studies.

Functional benefits of implants placed during ablative surgery: A 5‐year prospective study on the prosthodontic rehabilitation of 56 edentulous oral cancer patients

“…Literature shows that implant failure is low and equal for during‐ablative‐surgery and postponed‐placement protocols (3% to 10%) . Some authors speculate that in the during‐ablative‐surgery‐protocol, backscattering might increase the risk of implant failure or osteoradionecrosis because of higher irradiation doses in the bone adjacent the implants, although no in vivo studies so far have demonstrated such negative effects.…”

Can gamma irradiation during radiotherapy influence the metal release process for biomedical CoCrMo and 316L alloys?

“…Reports and reviews on failed implants or insufficient osseointegration after/during radiotherapy for both hip joints and dental implants indicate risks of implant failure or loss of the implant upon irradiation, most probably due to tissue damage. These risks increase with increasing irradiation dose . This has been questioned in some recent reviews and studies, and patients that undergo radiotherapy have been recommended dental implant therapy if following some guidelines (e.g., strict monitoring) .…”

Effectiveness of hyperbaric oxygen therapy in irradiated maxillofacial dental implant patients: A systematic review with meta-analysis

“…Reduced tissue healing capacity leads to osteoradionecrosis, necrotic bone exposure, and pathological fracture in response to tissue trauma; thus, with reduced healing ability and osteoradionecrosis in response to injury, the implant survival rate may be reduced for the maxillofacial oral cancer patients who have undergone radiotherapy treatment. [123456]…”