Background.-Adults with chronic respiratory conditions, specifically asthma and/or chronic obstructive pulmonary disease (COPD) may be at risk for poor oral health due to systemic inflammation, challenges in routine dental care, and side effects of medications used to treat these conditions. We examined the association of asthma, COPD, and co-existing asthma and COPD (asthma-COPD overlap syndrome, or ACOS) with tooth loss among US adults.Methods.-Cross-sectional design was employed using 2016 Behavioral Risk Factor Surveillance System data (N=387,217). Number of missing permanent teeth was categorized into 4 groups: 1)asthma only (N = 38,817); 2)COPD only (N = 19,819); 3)ACOS (N=13,494); and 4)no asthma, no COPD (N =315,087). Adjusted multinomial logistic regressions examined association between asthma/COPD categories and tooth loss.