Dental pain management – a cause of significant morbidity due to paracetamol overdose

O'Sullivan, Laura; Ahmed, Nabeela; Sidebottom, Andrew J.

doi:10.1038/sj.bdj.2018.264

Cited by 14 publications

(15 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The strategies included in this research coincide with the ones reported in similar studies, 10,12,13 especially with regard to the recurrence of the use of herbs, selfmedication, search for dental care, and eventually extraction. 16,22 In this study, as well as in the literature, self-medication is common for pain relief until the patient decides to consult a dentist. 16,22 It is interesting to note that results of this and other studies 12 highlight the relative importance of alcohol (both as local medication and intake) as a pain reliever.…”

Section: Discussionmentioning

confidence: 90%

“…As a summary, although the practices of pain relief described in this study have been documented in the literature of other countries, with different levels of scope and specificity, there is a general agreement regarding the following aspects: the practices are performed to cope with toothache; they are associated to a latency period before dental consultation; self-medication is the most prevalent practice of choice, which ends up with emergency tooth extraction. 22 With regard to the limitations of the study, it did not analyze the prevalence of the practices with the social determinants of health such as ethnicity, gender, poverty, or access to health services, specifically in the central area of Chile, where the study was carried out. 4 Neither was investigated the epidemiological subpopulation of the private health network, nor the one who do not have access to care.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

What do people do before going to the dentist? Qualitative study of cultural practices of pain relief in primary care.

et al. 2018

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

What do people do before going to the dentist? Qualitative study of cultural practices of pain relief in primary care.

et al. 2018

View full text Add to dashboard Cite

show abstract

“…The problem of overdose with paracetamol is frequently reported by previous studies [ 25 – 27 ]. In a recent study by O’Sullivan et al (2018) found that 38% of overdose patients treated in accident and emergency departments are caused by dental pain [ 25 ]. We recommend that dentists should refer to relevant guidelines on prescribing analgesics for dental pain [ 28 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

“…Paracetamol (also known as acetaminophen) was the most commonly used analgesic by patients with dental pain in this study. Paracetamol decreases acute dental pain [ 24 ] and is commonly used by patients who have dental pain [ 25 – 27 ]. The problem of overdose with paracetamol is frequently reported by previous studies [ 25 – 27 ].…”

Section: Discussionmentioning

confidence: 99%

“…Paracetamol decreases acute dental pain [ 24 ] and is commonly used by patients who have dental pain [ 25 – 27 ]. The problem of overdose with paracetamol is frequently reported by previous studies [ 25 – 27 ]. In a recent study by O’Sullivan et al (2018) found that 38% of overdose patients treated in accident and emergency departments are caused by dental pain [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Association between beliefs about medicines and self-medication with analgesics among patients with dental pain

et al. 2018

View full text Add to dashboard Cite

Self-medication with analgesics in dental pain management is a common practice as most of these medicines are available over-the-counter (OTC). The study aims to examine the relationship between beliefs about medicines and self-medication with analgesics in dental pain management in Malaysia. This cross-sectional study was conducted among conveniently sampled patients attending dental clinics, located in Kuala Lumpur, Malaysia to assess association between self-medication with analgesics and patient’s beliefs about medicines via Beliefs about Medicines Questionnaire. Participants were evaluated for their self-medication practices via 4 items. Further assessment was done via Quantitative Analgesic Questionnaire (QAQ) regarding the analgesics taken. Statistical analyses were performed using SPSS version 24, with 0.05 as level of significance. The prevalence of self-medication with analgesics was 29.4%, with 95.6% of the participants took analgesics when necessary. Participants practising self-medication for dental pain reported more positive beliefs in General-Necessity (13.04 vs. 9.98, p = 0.001) than those not practising self-medication. However, these participants had weaker beliefs in General-Harm (12.00 vs. 10.29, p = 0.006) and General-Overuse (11.38 vs. 10.31, p = 0.032) than those not practising self-medication. Participants beliefs in General-Harm (r = -0.243; p = 0.003) and General-Overuse (r = -0.203; p = 0.012) were negatively correlated with total QAQ point. The study found that individuals who practised self-medication had stronger beliefs about the benefits of medicines and weaker beliefs in viewing medicines as harmful and overused. Findings can guide public education to improve the safety aspects of self-medication with analgesics in dental practice.

show abstract

Fatal acetaminophen poisoning with hepatic microvesicular steatosis in a child after repeated administration of therapeutic doses

Bouvet

Cauchois

Baert

et al. 2020

Forensic Science International

View full text Add to dashboard Cite

Acetaminophen is the leading cause of acute liver failure worldwide following massive ingestion. We present here a fatal acute liver failure after repeated administration of four therapeutic doses of acetaminophen at 4-hour intervals in a previously healthy 9-year-old female who presented dental pain after a facial trauma during sport practice. A diagnosis of paracetamol-induced hepatitis was deduced from the clinical picture of fulminant hepatitis and tubular necrosis, the encephalopathy with oedema and without signs of trauma. Liver biopsy showed typical acetaminophen-induced necrosis and a microvesicular steatosis in periportal hepatocytes. These injuries might have been favored by pre-existing mitochondrial J o u r n a l P r e -p r o o f dysfunction related, for instance, to a deficiency in an enzyme of the mitochondrial oxidation pathway, or the respiratory chain. The observation of microvesicular steatosis in the periportal areas suggests an increased vulnerability via pre-existing mitochondrial dysfunction. As the liver status of patients is mostly unknown, the frequency of administration (every six hours) must be respected and the use of pharmaceutical forms allowing to adjust the dose as closely as possible to the child's weight should be promoted.

show abstract

Dental pain management – a cause of significant morbidity due to paracetamol overdose

Cited by 14 publications

References 8 publications

What do people do before going to the dentist? Qualitative study of cultural practices of pain relief in primary care.

What do people do before going to the dentist? Qualitative study of cultural practices of pain relief in primary care.

Association between beliefs about medicines and self-medication with analgesics among patients with dental pain

Fatal acetaminophen poisoning with hepatic microvesicular steatosis in a child after repeated administration of therapeutic doses

Contact Info

Product

Resources

About