Dental Stem Cell Differentiation Toward Endodermal Cell Lineages: Approaches to Control Hepatocytes and Beta Cell Transformation

Gnanasegaran, Nareshwaran; Govindasamy, Vijayendran; Nathan, Prakash; Musa, Sabri; Kasim, Noor Hayaty Abu

doi:10.1007/978-3-319-28947-2_12

Cited by 1 publication

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References 137 publications

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“…The MSCs of dental tissues instead of progenitors exhibit the minimal characterization criteria for human stem cells well-defined by the International Society for Cellular Therapy (ISCT) [162]. The differentiation of these cells into various cell lineages including hepatocytes [284], osteogenic [285], and neurogenic cells [286] has been confirmed. Among these cells, DPSCs have been extensively studied for use in hard TE [288].…”

Section: General Informationmentioning

confidence: 95%

Bone Tissue Engineering Using Human Cells: A Comprehensive Review on Recent Trends, Current Prospects, and Recommendations

et al. 2019

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The use of proper cells for bone tissue engineering remains a major challenge worldwide. Cells play a pivotal role in the repair and regeneration of the bone tissue in vitro and in vivo. Currently, a large number of differentiated (somatic) and undifferentiated (stem) cells have been used for bone reconstruction alone or in combination with different biomaterials and constructs (e.g., scaffolds). Although the results of the cell transplantation without any supporting or adjuvant material have been very effective with regard to bone healing. Recent advances in bone scaffolding are now becoming new players affecting the osteogenic potential of cells. In the present study, we have critically reviewed all the currently used cell sources for bone reconstruction and discussed the new horizons that are opening up in the context of cell-based bone tissue engineering strategies.

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