DEPDC1B: A novel tumor suppressor gene associated with immune infiltration in colon adenocarcinoma
Dandan Zhu,
Huolun Feng,
Zhixiong Zhang
et al.
Abstract:BackgroundRecent research indicates a positive correlation between DEP structural domain‐containing 1B (DEPDC1B) and the cell cycle in various tumors. However, the role of DEPDC1B in the infiltration of the tumor immune microenvironment (TIME) remains unexplored.MethodsWe analyzed the differential expression and prognostic significance of DEPDC1B in colon adenocarcinoma (COAD) using the R package “limma” and the Gene Expression Profiling Interactive Analysis (GEPIA) website. Gene set enrichment analysis (GSEA)… Show more
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