Depigmentation of the normally pigmented patches in universal vitiligo patients by cryotherapy

Radmanesh, Mohammad

doi:10.1046/j.1468-3083.2000.00038.x

Cited by 35 publications

(37 citation statements)

References 7 publications

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“…14 In this method, a closed contact CO 2 cryogun unit with a round, at-topped cryoprobe was chosen. The reasons for this selection instead of using the more popular liquid nitrogen cryotherapy were its easy control and monitoring.…”

Section: Methodsmentioning

confidence: 99%

Naevus of Ota treatment with cryotherapy

Radmanesh¹

2001

Journal of Dermatological Treatment

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Section: Methodsmentioning

confidence: 99%

Naevus of Ota treatment with cryotherapy

Radmanesh¹

2001

Journal of Dermatological Treatment

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“…[18] CRYOTHERAPY When rapid depigmentation is desirable, physical agents like cryotherapy and lasers work faster than bleaching agents. Radmanesh [24] has demonstrated the use of cryosurgery for cost-effective rapid depigmentation that is permanent and has excellent cosmetic result but only over limited areas at a time.…”

Section: Q-switched Alexandrite Laser (755 Nm)mentioning

confidence: 99%

Depigmentation therapies in vitiligo

Gupta

Kumari

Thappa

2012

Indian J Dermatol Venereol Leprol

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Depigmentation therapy in vitiligo is an option in those with extensive vitiligo who have failed to respond to medical therapy and have obvious cosmetic disfigurement due to intervening patchy pigmented areas. Various aspects of this therapy such as the cost, treatment time, course, permanency of depigmentation, side effects, and the possibility of repigmentation should first be discussed with the patient. At present, there is no ideal depigmenting therapy available, but many agents in the market have been in use for many years. Monobenzyl ether of hydroquinone (MBEH) is the mainstay and Food and Drug Administration (FDA) approved in USA but takes many months to depigment and is associated with local side effects and risk of repigmentation. Other agents which are also used are 4-methoxy phenol and 88% phenol. Physical therapies for depigmentation include Q-switched ruby and alexandrite lasers and cryotherapy. Second-line agents which can be explored for depigmentation include imatinib mesylate, imiquimod, and diphencyprone. Many possible experimental agents are being explored like various phenol derivatives, melanoma vaccines, interferon gamma, busulfan, etc. A major lacuna still exists in this area and a lot more research is desirable to give satisfactory cosmesis to these patients with extensive vitiligo.

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“…Dört-metoksifenol de MBEH gibi melanotoksiktir. Her iki tedavi de Q-switched ruby lazer ve kriyoterapi ile kombine kullan labilir (21,22).…”

Section: Depigmentasyonunclassified

Treatment of Vitiligo and New Treatment Approaches

Demirel¹,

Borlu²

2010

Turk J Dermatol

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ÖzetVitiligo, melanositlerin sayı ve işlev kaybı ile karakterize bir pigment hastalığıdır. Etyolojisi bilinmemektedir ancak otoimmun, genetik, biyokimyasal faktörler ve nöral mekanizmalar etyolojide suçlanmaktadır. Melanosit antijenlerini hedef alan sitotoksik T hücrelerinin varlığı ve sitokin seviyelerindeki dengesizliğin melanosit hasarına ve ölümüne neden olduğu düşünülmektedir. Vitiligo tedavisi lezyonların yaygınlığına, lokalizasyonuna, yaşa ve önceki tedavilere verilen yanıta göre değişmektedir. Bu derlemede vitiligo tedavisi geleneksel tedaviler, yeni tedavi seçenekleri, cerrahi tedaviler, deneysel ve diğer tedavi seçenekleri başlıkları altında ele alınmış ve güncel literatür bilgileri ışığında değerlendirilmiştir. (Turk J Dermatol 2010; 4: 33-9 AbstractVitiligo is an pigmentary disorder characterized by loss of functional melanocytes. Altough the aetiology is unknown, autoimmunity, genetic factors, biochemical factors and neural mechanisms were suspected. Cytotoxic T cells targeting melanocyte antigens are present and also an imbalance of the cytokine levels leading to melanocyte damage and death. It is believed that the treatment of vitiligo differs according to the severity of disease, localisation, age and response to previous medications. In this article we reviewed the current literature about vitiligo and classified the treatment options of vitiligo as traditional and current treatment options, surgical treatments, experimental therapies and other treatment options. (Turk J Dermatol 2010; 4: 33-9)

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Depigmentation of the normally pigmented patches in universal vitiligo patients by cryotherapy

Abstract: Cryotherapy is a cost effective, non-complicating, easily available procedure which can be used for depigmentation of normally pigmented patches in patients with universal vitiligo.

Cited by 35 publications

References 7 publications

Naevus of Ota treatment with cryotherapy

Naevus of Ota treatment with cryotherapy

Depigmentation therapies in vitiligo

Treatment of Vitiligo and New Treatment Approaches

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