Deployment of drug‐eluting stents for isolated proximal lad disease is associated with lower major adverse cardiac events and no increase in stent thrombosis when compared with bare metal stents: A 5‐year observational cohort study

Abstract

When treating proximal LAD disease, use of DES was associated with a lower MACE rate than BMS, with no differences in the incidence of stent thrombosis, myocardial infarction or 5 year all cause mortality. Our data suggests that despite the adverse prognostic correlates of proximal LAD disease, DES deployment in this location is both safe and clinically more effective than BMS.

In-hospital outcomes and mortality in octogenarians after percutaneous coronary intervention

“…Since, in elderly patients, the most common appearance of CAD is multivessel and small arteries disease those patients are at higher risk of restenosis, so DES should be used. However, in our study and in previously conducted studies an opposite trend in procedural strategy was observed [24,25]. In the most recent data presented by Puymirat et al [26] it was proven that DES implantation was as safe as BMS; these authors also indicate lower rates of target vessel revascularisation in very old patients.…”

Evaluation of the Incidence of Major Adverse Cardiac and Cerebrovascular Events after Percutaneous Coronary Intervention or Coronary Artery Bypass Graft on Proximal Left Anterior Descending Artery with and without Other Coronary Arteries Involvement

“…Experts also believe that PCI on proximal LAD should be performed with DES. Similarly, Jones et al reported lower MACCE rates with no increase in the incidence of stent thrombosis while using DES in comparison to BMS in significant proximal LAD stenosis (12).…”

Second generation drug‐eluting stents versus bare‐metal stents for percutaneous coronary intervention of the proximal left anterior descending artery: An analysis of the BASKET‐PROVE I and II trials

“…PCI with DES is the current treatment of choice for patients with isolated proximal LAD coronary artery disease, judged from the fact that this procedure is performed up to seven times more frequently than surgery , which might explain the lack of interest in conducting further randomized trials in this specific population. The present report presents important information, since data on patients undergoing proximal LAD PCI with modern devices and new antiplatelet drugs are limited .…”