In this work, we present the substrate temperature influenced change in the structural, optical, morphological, and electrical conductivity properties of CdIn 2 S 4 thin films deposited on amorphous glass substrates by nebulized spray pyrolysis (NSP) technique. X-ray diffraction pattern revealed that the asdeposited CdIn 2 S 4 thin films had a cubic structure with a preferred orientation along (111) plane. The reduced strain by increasing the substrate temperature from 200 to 350 • C increased the average crystalline size from 17 to 33 nm while the formation of secondary phases such as CdIn 2 O 4 and In 2 O 3 reduced it to 21 nm after the substrate temperature at 450 • C. The energy dispersive analysis by X-ray (EDAX) studies confirmed the presence of Cd, In, and S. The absorption coefficient, direct band gap energy, Urbach energy, skin depth, and extinction coefficient of CdIn 2 S 4 films were analyzed by optical absorption spectra. The better conductivity and mobility noticed at T s = 350 • C are explained by carrier concentration and crystalline size. Better optical and electrical conductivity behavior of CdIn 2 S 4 thin film sample suggests for effective PEC solar cell fabrication.