Deposition effect of inhaled particles in the human: Accurate health risks of personal exposure to PAHs and their derivatives from residential solid fuel combustion

Feng, Rong; Xu, Hongmei; Gu, Yan; Gao, Min; Bai, Yunlong; Liu, Meixuan; Shen, Zhenxing; Sun, Jian; Qu, Linli; Ho, Steven Sai Hang; Cao, Junji

doi:10.1016/j.atmosenv.2022.119510

Cited by 11 publications

(1 citation statement)

References 63 publications

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“…Second, in addition to heavy metals, other air pollutants such as polycyclic aromatic hydrocarbons (PAHs) can bind to fine particles. These chemical components can further react with each other to form toxic derivatives that may lead to health damage in humans. , Third, urinary heavy metals and biomarkers may not provide a comprehensive assessment of human exposure and health implications of heavy metals. The potential interaction of metals and the nonlinear relationship between metals and biomarkers have led to the health effects of mixed metals becoming more complex and elusive.…”

Section: Resultsmentioning

confidence: 99%

Health Effects of Combined Respiratory and Internal Exposure to Multiple Metals in PM_2.5 and PM_0.25 in Solid Fuel Combustion Household Environment

Gu,

Xu,

Liu

et al. 2024

ACS EST Air

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Respiratory exposure to heavy metals is an important health risk factor; however, the impact of co-exposure to multiple metals on internal exposure and health remains unclear. Here, we evaluated the relationship between exposure to nine metals (K, Ca, Fe, Cr, Mn, Zn, Pb, Se, and Hg) in PM2.5, PM0.25, and urinary metals with health biomarkers, i.e., 8-hydroxy-2′-deoxyguanosine (8-OHdG), vascular endothelial growth factor (VEGF), interleukin-8 (IL-8), and C-reactive protein (CRP), in rural housewives in Yuncheng City, northern China. K, Ca, Cr, Mn, Zn, and Hg were primarily present in PM0.25. Fe, Pb, and Se showed the higher concentrations in PM2.5, indicating that these elements mainly existed in the coarser fraction of PM2.5. The correlation of metals in the two particle sizes was decent, but only K and Se in PM2.5 and PM0.25 were significantly correlated with their respective concentrations in urine. Most metals in the urine were negatively correlated with biomarkers representing inflammation and oxidative stress. Based on the Bayesian kernel machine regression mixed effect model, we found that the co-exposure of nine metals in PM0.25 was significantly negatively correlated with VEGF, with Hg and Cr having the highest posterior inclusion probability, which may be due to the synergistic effect of these two metals. We recommend minimizing the use of solid fuels at home and regularly replacing utensils, which can have a certain effect on reducing exposure to heavy metals. This study offers a theoretical foundation and practical exposure case for quantitatively assessing the effects of particulate matter-bound metals on human health during the combustion of solid fuels in rural households.

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Section: Resultsmentioning

confidence: 99%

Health Effects of Combined Respiratory and Internal Exposure to Multiple Metals in PM_2.5 and PM_0.25 in Solid Fuel Combustion Household Environment

Gu,

Xu,

Liu

et al. 2024

ACS EST Air

Self Cite

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Day–night variation, size distribution, source identification, and health risk of polycyclic aromatic hydrocarbons in particulate matter in Ulsan, South Korea

Do,

Vuong,

Nwankwo

et al. 2024

Atmospheric Environment

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Personal exposure of women to PM2.5-bound PAH derivatives from cooking emissions in varied rural kitchen setups

Deepthi,

Passi,

Chithra

et al. 2025

Building and Environment

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Deposition effect of inhaled particles in the human: Accurate health risks of personal exposure to PAHs and their derivatives from residential solid fuel combustion

Cited by 11 publications

References 63 publications

Health Effects of Combined Respiratory and Internal Exposure to Multiple Metals in PM_2.5 and PM_0.25 in Solid Fuel Combustion Household Environment

Health Effects of Combined Respiratory and Internal Exposure to Multiple Metals in PM_2.5 and PM_0.25 in Solid Fuel Combustion Household Environment

Day–night variation, size distribution, source identification, and health risk of polycyclic aromatic hydrocarbons in particulate matter in Ulsan, South Korea

Personal exposure of women to PM2.5-bound PAH derivatives from cooking emissions in varied rural kitchen setups

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Deposition effect of inhaled particles in the human: Accurate health risks of personal exposure to PAHs and their derivatives from residential solid fuel combustion

Cited by 11 publications

References 63 publications

Health Effects of Combined Respiratory and Internal Exposure to Multiple Metals in PM2.5 and PM0.25 in Solid Fuel Combustion Household Environment

Health Effects of Combined Respiratory and Internal Exposure to Multiple Metals in PM2.5 and PM0.25 in Solid Fuel Combustion Household Environment

Day–night variation, size distribution, source identification, and health risk of polycyclic aromatic hydrocarbons in particulate matter in Ulsan, South Korea

Personal exposure of women to PM2.5-bound PAH derivatives from cooking emissions in varied rural kitchen setups

Contact Info

Product

Resources

About

Health Effects of Combined Respiratory and Internal Exposure to Multiple Metals in PM_2.5 and PM_0.25 in Solid Fuel Combustion Household Environment

Health Effects of Combined Respiratory and Internal Exposure to Multiple Metals in PM_2.5 and PM_0.25 in Solid Fuel Combustion Household Environment