During the field application of pesticides by plant protection UAV, due to the interference of meteorological factors or operating parameters, the deposition effect of droplets is poor. In order to explore the impact of the nozzle angle of plant protection UAV on droplet deposition distribution, this article is based on field experiments and collects data on different flight speeds (1, 3, 5 m/s) and nozzle angles (±60°, ±45°, ±30°, 0°), and performs variance analysis and regression analysis on the test results. The results showed that adjusting the nozzle angle had a significant effect on the amount of droplet deposition and deposition uniformity. Compared with 0°, the nozzle angle of -30° increased the amount of deposition by 76.94% and 61.04% at flight speeds of 1.2 m/s and 3 m/s, respectively. The flight speed had a significant effect on the amount of droplet deposition, and the increase in flight speed decreased the amount of droplet deposition by 55.97%-77.06% and had no significant effect on the uniformity of droplet deposition. This study provides a reference for improving the droplet deposition effect of plant protection UAV field pesticide application operations.