Depressed Mood Differentially Mediates the Relationship between Pain Intensity and Pain Disability Depending on Pain Duration: A Moderated Mediation Analysis in Chronic Pain Patients

Probst, Thomas; Neumeier, Susanne; Altmeppen, J.; Angerer, Michael; Loew, Thomas H.; Pieh, Christoph

doi:10.1155/2016/3204914

Cited by 22 publications

(26 citation statements)

References 44 publications

(61 reference statements)

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“…Despite no statistically significant differences between samples, we included depression, muscle pain, and ART adherence in the model based on theoretical considerations that they influence disability. 14,28-30 CD4 count, although statistically different between countries, was not included because the mean values were similar from a clinical perspective.…”

Section: Resultsmentioning

confidence: 99%

Functional Limitations and Disability in Persons Living with HIV in South Africa and United States: Similarities and Differences

Kietrys

Myezwa

Galantino

et al. 2019

J Int Assoc Provid AIDS Care

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Persons living with HIV (PLHIV) may experience disability. We compared disability among PLHIV in the United States and South Africa and investigated associations with health and demographic characteristics. Secondary analysis of cross-sectional data using medical records and questionnaires including the World Health Organization Disability Assessment Schedule (WHO-DAS) 2.0 12-item version (range: 0-36, with higher scores indicative of more severe disability). Between-country differences for the presence of disability were assessed with logistic regression and differences in severity using multiple regression. Eighty-six percent of US participants reported disability, compared to 51.3% in South Africa. The mean WHO-DAS score was higher in the United States (12.09 ± 6.96) compared to South Africa (8.3 ± 6.27). Participants with muscle pain, depression, or more years since HIV diagnosis were more likely to report disability. Being female or depressed was associated with more severity. Being adherent to anti-retroviral therapy (ART) and employed were associated with less severity. Because muscle pain and depression were predictive factors for disability, treatment of those problems may help mitigate disability in PLHIV.

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Section: Resultsmentioning

confidence: 99%

Functional Limitations and Disability in Persons Living with HIV in South Africa and United States: Similarities and Differences

Kietrys

Myezwa

Galantino

et al. 2019

J Int Assoc Provid AIDS Care

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“…One such variable is, for example, cognitive ability, which has already been shown to mediate the relationship between symptoms and functioning in patients with traumatic brain injury [46]. Moreover, personal (e.g., gender) and environmental (e.g., family, work) variables belonging to the ICF contextual factors might moderate the mediating effects of mentalization and/or self-efficacy as might aspects of the disorder such as duration of illness [47] or the specific mental diagnosis. As the diagnoses were made by the therapeutic staffs in the present study and the validity of such "routine clinical diagnoses" is still a matter of debate [48], we abstained from analyzing this research question.…”

Section: Discussionmentioning

confidence: 99%

Mentalization and Self-Efficacy as Mediators between Psychological Symptom Severity and Disabilities in Activities and Participation in Psychotherapy Patients

Probst

Dehoust²,

Brütt

et al. 2018

Psychopathology

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Background: Psychotherapy patients can be more or less disabled by their psychological symptoms. The present study investigated whether mentalization and self-efficacy contribute to the association between psychological symptom severity and disabilities in activities and participation. Methods: The data of 216 psychotherapy inpatients were examined in a cross-sectional design. Bootstrapping-enhanced mediation analyses were performed to investigate whether self-efficacy and mentalization are mediators between psychological symptom severity and disabilities in activities and participation. The Hamburg Modules for the Assessment of Psychosocial Health-49 were used to measure psychological symptom severity and self-efficacy, mentalization was assessed with the Mentalization Questionnaire, and disabilities in activities and participation were operationalized with the ICF-Mental-A & P questionnaire. Results: Mentalization as well as self-efficacy functioned as mediators between psychological symptom severity and disabilities in activities and participation (p < 0.05). They were equally strong mediators, and both remained significant mediators when statistically controlling for the other mediator (p < 0.05). Conclusions: Mentalization as well as self-efficacy explain a significant proportion of the relationship between psychological symptom severity and disabilities in activities and participation. Working on mentalizing and self-efficacy might be important mechanisms to reduce disability due to symptoms. The cross-sectional design is a limitation of the study.

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“…Moderated mediation analyses (Hayes, 2013; Probst et al, 2016) are needed in the future to evaluate whether the contribution of pre- and peritraumatic factors on the development of PTSD symptoms is different for e.g. different age groups.…”

Section: Discussionmentioning

confidence: 99%

Peritraumatic distress fully mediates the relationship between posttraumatic stress symptoms preoperative and three months postoperative in patients undergoing spine surgery

Shiban

Lehmberg

Hoffmann

et al. 2018

European Journal of Psychotraumatology

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Background: Growing evidence shows the significance of illness and surgical procedures as traumatizing stressors. Risk factors are widely investigated in various settings and samples, using numerous measures of posttraumatic stress and posttraumatic stress disorder (PTSD). While pretrauma psychological distress is acknowledged as an influential factor, peritraumatic experiences are controversially still being discussed as relevant to the development of PTSD. Objective: In a group of patients consecutively undergoing elective spine surgery (N = 89) in a German hospital, this longitudinal study addressed the question of how pretrauma PTSD symptoms and peritrauma distress interact with one another in regard to the amount of posttrauma symptoms of PTSD. Methods: Pre- and posttrauma symptoms of PTSD as well as peritrauma distress were assessed through questionnaires one week before, one week after or three months after surgery. Results: Even though all three variables showed significant correlations with one another, mediation analysis revealed that peritrauma distress fully mediated the relationship between pre- and posttrauma PTSD symptoms. Conclusions: These results add new insights to the controversial discussion on the role peritraumatic experiences play in the development of PTSD, especially in medical settings.

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Depressed Mood Differentially Mediates the Relationship between Pain Intensity and Pain Disability Depending on Pain Duration: A Moderated Mediation Analysis in Chronic Pain Patients

Cited by 22 publications

References 44 publications

Functional Limitations and Disability in Persons Living with HIV in South Africa and United States: Similarities and Differences

Functional Limitations and Disability in Persons Living with HIV in South Africa and United States: Similarities and Differences

Mentalization and Self-Efficacy as Mediators between Psychological Symptom Severity and Disabilities in Activities and Participation in Psychotherapy Patients

Peritraumatic distress fully mediates the relationship between posttraumatic stress symptoms preoperative and three months postoperative in patients undergoing spine surgery

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