Depression after stroke: a review of the evidence base to inform the development of an integrated care pathway. Part 2: Treatment alternatives

Turner-Stokes, Lynne; Hassan, Nibras

doi:10.1191/0269215502cr488oa

Cited by 66 publications

(36 citation statements)

References 62 publications

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“…This questionnaire consists of 21 items answered on a 4-point scale, with the score ranging from 0 to 63 and higher scores indicating more severe depression (0-13 = no or minimal depression, 14-19 = mild depression, 20-28 = moderate depression and 29-63 = severe depression) (20). Since there is little emphasis on somatic symptoms, this is one of the most useful tools to evaluate depression post-stroke (21). It also has good psychometric properties and is sensitive to change in the population with stroke (22).…”

Section: Measuring Instrumentsmentioning

confidence: 99%

Changes in life habits affected by mild stroke and their association with depressive symptoms

Rozon¹,

Rochette²

2015

J Rehabil Med

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Section: Measuring Instrumentsmentioning

confidence: 99%

Changes in life habits affected by mild stroke and their association with depressive symptoms

Rozon¹,

Rochette²

2015

J Rehabil Med

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“…20 • Selective serotonin re-uptake inhibitors (SSRIs) appear generally to be about as effective as tricyclic antidepressants (TCAs), but have fewer reported side-effects, 21 and are probably therefore cost efficient despite the slightly higher drug costs. 22 Table 2.…”

Section: The Evidence For Use Of Antidepressants In People With Abimentioning

confidence: 99%

Use of antidepressant medication following acquired brain injury: concise guidance

Turner-Stokes

MacWalter

2005

Clinical Medicine

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Introduction and aimsAcquired brain injury (ABI) -whether due to stroke, trauma or any other cause -is frequently complicated by depression, which can interfere with rehabilitation, leading to poorer outcomes. The use of antidepressants in the treatment of depression following ABI is increasingly widespread. Because it may not be practical to involve a psychiatrist in all cases, first line management is usually undertaken by general clinicians. However, at present, many people are given antidepressant medication as a matter of routine -often without their knowledge and without any clear treatment plan.The aim of these guidelines is to provide the general physician, GP or other clinician with a safe approach to managing minor to moderate depression in the context of rehabilitation or recovery from ABI, and to identify those individuals who require referral to mental health services.The guidelines focus on the use of antidepressant drugs, but these are by no means the only way to manage depression following ABI, and it is important in any event to consider other contributing factors before reaching for the prescription pad. Alternative interventions may include simple measures to address environmental or other factors which contribute to low mood (such as missing their home and family, or worries about life outside hospital), and non-pharmacological interventions, such as 'talking therapies' , for patients who have the cognitive and communicative abilities to engage successfully.The guidelines have been prepared in accordance with the principles laid down by the AGREE Collaboration (Appraisal of Guidelines for REsearch and Evaluation). 1 A summary of the guideline development process is given in Table 1. Although developed specifically with brain injury in mind, the main principles applied here may also be applicable in other conditions, especially where the person's ability to interact is impaired.I CLINICAL GUIDANCE 268

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“…The fact that they are 'understandable' or consist of symptoms that may be a direct consequence of brain injury (eg apathy) should not prevent a trial of an antidepressant. Several antidepressants have been shown to be effective in post-stroke depression 7 . Selective serotonin reuptake inhibitors (SSRIs), which have fewer side effects, are a reasonable first choice for depression after stroke or TBI (Table 3).…”

Section: Mood Disordersmentioning

confidence: 99%

Neuropsychiatry

Fleminger

Dilley

2002

Clinical Medicine

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Depression after stroke: a review of the evidence base to inform the development of an integrated care pathway. Part 2: Treatment alternatives

Abstract: A suggested regimen for the use of sertraline in PSD was put forward. Development of an ICP may help to establish a more consistent approach to assessment and treatment of PSD, and form a basis for future comparison of different treatments as they become available.

Cited by 66 publications

References 62 publications

Changes in life habits affected by mild stroke and their association with depressive symptoms

Changes in life habits affected by mild stroke and their association with depressive symptoms

Use of antidepressant medication following acquired brain injury: concise guidance

Neuropsychiatry

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