Depression and hospital admission in older patients with head and neck cancer: analysis of a national healthcare database

Laurence, Brian; Mould‐Millman, Nee‐Kofi; Nero, Kenneth E.; Salter, Reginald O.; Sagoo, Paramjeet K.

doi:10.1111/ger.12247

Cited by 19 publications

(30 citation statements)

References 9 publications

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“…117 Over the course of RT, patients report increases in depression and anxiety, 118–122 pain, 118 and reductions in sleep quality 122 and QOL. 123,124 In a sample of HNSCC patients age ≥50 years, a diagnosis of depression was associated with 28% increase in the likelihood of hospital admission following an emergency department visit for men and a 31% increase for women, 125 suggesting that psychosocial distress may have implications for medical treatment and healthcare utilization.…”

Section: Methodsmentioning

confidence: 99%

The Older Adult With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: Knowledge Gaps and Future Direction in Assessment and Treatment

Maggiore

Zumsteg

BrintzenhofeSzoc

et al. 2017

International Journal of Radiation Oncology*Biology*Physics

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Older adults with squamous cell carcinomas of the head and neck (HNSCC) pose unique treatment and supportive care challenges to oncologists and other cancer care providers. The majority of patients with HNSCC present with locoregionally advanced (LA) disease, for which combined modality treatment integrating chemotherapy and radiation therapy is often necessary to maximize tumor control. However, applying these approaches to an older population with concomitant comorbidities and higher risk for functional impairments remains challenging, and is exacerbated by the paucity of studies involving older adults. The purpose of this paper is to identify knowledge gaps in the evaluation and management of older adults with HNSCC and their caregivers, particularly those undergoing concurrent chemoradiation, through a review of the literature conducted by clinicians, researchers, and patient advocates. The findings highlight the importance of a geriatric assessment and the therapeutic paradigms and challenges relevant to this population. Furthermore, we identify the need for additional research and interventions related to key supportive care issues that arise during and after treatment in older adults with LA-HNSCC. Based on our findings, we prioritized these issues to guide future patient-oriented research endeavors to address these knowledge gaps and thus better serve this growing patient population.

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Section: Methodsmentioning

confidence: 99%

The Older Adult With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: Knowledge Gaps and Future Direction in Assessment and Treatment

Maggiore

Zumsteg

BrintzenhofeSzoc

et al. 2017

International Journal of Radiation Oncology*Biology*Physics

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“…Maternal records were linked capturing in- or out-patient hospital care 1–3 years prior to or after delivery (i.e., 2007 – 2011). ( 21 ) Specifically, mothers were categorized as having antenatal depression if they had any linkable in- or out-patient discharge records with relevant International Code for Diseases (ICD-9-CM 296.X; 311; 300.4; 648.4X)( 22 ) in the 3 years preceding delivery of the index birth (i.e. ‘Antenatal depression : SPARCS’).…”

Section: Methodsmentioning

confidence: 99%

“…Maternal records were linked to capture in‐ or outpatient hospital care 1 to 3 years prior to or after delivery (i.e., 2007‐2011) . Specifically, mothers were categorized as having antenatal depression if they had any linkable in‐ or outpatient discharge records with relevant International Classification of Diseases, Ninth Revision, Clinical Modification codes (296.X; 311; 300.4; 648.4X) in the 3 years preceding delivery of the index birth (i.e., “Antenatal depression: SPARCS”). Any in‐ or outpatient discharge records up to 3 years after delivery from SPARCS were used to define postnatal depression (i.e., “Postnatal depression: SPARCS”).…”

Section: Methodsmentioning

confidence: 99%

Timing of Maternal Depression and Sex‐Specific Child Growth, the Upstate KIDS Study

Park

Sundaram

Gilman

et al. 2017

Obesity

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Objective Equivocal findings have been reported between maternal depression and children’s growth possibly given limited attention to its disproportionate impact by child sex. We assessed the relationship between the timing of maternal depression and children’s growth in a population-based prospective birth cohort with particular attention to sex differences. Methods The Upstate KIDS Study comprised 4,394 children followed through 3 years of age from 2008 to 2010. Maternal depression was measured antenatally by linkage with hospital discharge records before delivery, and postnatally, by depressive symptoms reported from questionnaires. Child’s growth was measured by sex-and-age-specific weight, height, weight-for-height, and body mass index. Adjusted linear mixed effects models were used to estimate growth outcomes for the full sample and separately by plurality and sex. Results Antenatal depression was associated with lower weight-for-age (−0.24 z-score units; 95%CI: −0.43, −0.05) and height-for-age (−0.26; −0.51, −0.02) among singleton boys. Postnatal depressive symptoms were associated with higher weight-for-height (0.21; 0.01, 0.42) among singleton girls. Conclusions Our findings suggest that antenatal depression was associated with lower weight and smaller height only for boys, while postnatal depressive symptom was associated with higher weight-for- height only for girls. Timing of depression and the mechanisms of sex-specific responses require further examination.

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“…Depression and its sequalae pose a threat to survivorship among HNC patients . Besides its adverse effects on overall and cancer‐specific survival, depression significantly increases rates of hospital admission; risk of noncompliance with recommended treatment; poorer treatment response; malnutrition; and all‐cause mortality . It has also been linked to suicide among patients with HNC, relevant because HNC survivors have significantly higher risks of suicide compared with other cancer survivors and the general US population …”

Section: Introductionmentioning

confidence: 99%

Prevalence and sociodemographic factors associated with depression among hospitalized patients with head and neck cancer—Results from a national study

et al. 2018

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Depression and hospital admission in older patients with head and neck cancer: analysis of a national healthcare database

Abstract: Depression is associated with hospital admission among adults aged 50 and over with HNC.

Cited by 19 publications

References 9 publications

The Older Adult With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: Knowledge Gaps and Future Direction in Assessment and Treatment

The Older Adult With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: Knowledge Gaps and Future Direction in Assessment and Treatment

Timing of Maternal Depression and Sex‐Specific Child Growth, the Upstate KIDS Study

Prevalence and sociodemographic factors associated with depression among hospitalized patients with head and neck cancer—Results from a national study

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