Reassessing coping, a concept first proposed in Asia, refers to efforts to wait patiently for an appropriate opportunity to act or for a change or improvement in a situation, and can be observed in individuals facing stressful relationship events. The main purpose of the present study was to determine if reassessing coping would be associated with a lower risk of depression. The author examined the relationships between depression risk using the Center for Epidemiologic Studies Depression Scale (CES-D) and coping strategies for interpersonal stressors, including reassessing coping, in a sample of 1,912 Japanese college students. In our sample, the proportions of women and men with depressive symptoms were 55.28% (95% confidence intervals (CIs) [52.35, 58.20]) and 46.08% (95% CIs [42.63, 49.52]), respectively, using the conventional CES-D cut-off score of 16. A multivariate logistic regression analysis revealed that reassessing coping was significantly associated with a lower risk of depression (ORÂ =Â 0.92, 95% CIs [0.89, 0.95]), after adjusting for gender. Distancing coping (strategies to actively damage, disrupt, or dissolve a stressful relationship) and constructive coping (strategies to improve, maintain, or sustain a relationship without irritating others) were significantly associated with a greater depression risk. Reassessing coping for interpersonal stressors was associated with a low risk of depression among Japanese college students.Electronic supplementary materialThe online version of this article (doi:10.1186/s40064-015-1111-7) contains supplementary material, which is available to authorized users.