Depression and schizophrenia: Many biological and clinical similarities

Institutional Neglect of Anosognosia Is a Critical Barrier in the Treatment of Psychosis Related Disorders

“…It comes as no surprise that decades of drug development have produced dozens of antipsychotics that treat hallucinations but do little for patient insight or for negative symptoms in general. Complexities in schizophrenia are so challenging for researchers that most clinical trials fail, with only 20% to 30% of patients showing significant improvement over a placebo 2 …”

“…Complexities in schizophrenia are so challenging for researchers that most clinical trials fail, with only 20% to 30% of patients showing significant improvement over a placebo. 2 Psychiatrists, hospitals, and clinical staff are not well trained or equipped to manage patients with poor insight, and few institutions have effective protocols for engagement, medication, or therapies for anosognosia patients. The sickest psychiatric patients, those unable to recognize their illness, have been effectively carved out of the healthcare system.Obtaining life-saving medical care for patients with anosognosia has become increasingly difficult.…”