Depression, anxiety, and their relation with clinical parametersand androgen levels in hirsute women

Irak, Leyla; Yavuz, Hasan; Doğan, Berçem Ayçıçek; Mete, Türkan; Berker, Dilek; Güler, Serdar

doi:10.3906/sag-1405-72

Cited by 6 publications

(8 citation statements)

References 31 publications

(45 reference statements)

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“…Weber showed that correlation of serum testosterone is significant only in women with severe depression ( 23 ). Depression and the severity of depressive symptoms were positively correlated with dehydroepiandrosterone sulfate levels, not testosterone levels in an IRAK study ( 8 ). Hypothalamic-pituitary adrenal system dysregulation has an important role in the pathophysiology of depression that is reflected by an increased secretion of adrenal hormones, especially cortisol and dehydroepiandrosterone ( 23 ).…”

Section: Discussionmentioning

confidence: 96%

“…Also, regular exercise and using drugs such as metformin may be a potential confounder of the relationship between depression and insulin resistance that were neglected in our study. Association between depression and testosterone level has been evaluated in several studies with conflicting results ( 6 , 8 , 10 , 17 ). In the present study, there is no correlation between testosterone level and depression in PCOS and non-PCOS women and all of the population.…”

Section: Discussionmentioning

confidence: 99%

“…Correct diagnosis and treatment of PCOS can prevent future metabolic, endocrine, and cardiovascular outcomes and decrease psychological stresses ( 5 , 7 ). Women with hyperandrogenism syndrome are at increased risk for mood disorders that may be due to the relationship between androgen levels and depression ( 8 ). Some studies reported a significant increase in prevalence of depression among PCOS women compared with the controls ( 3 , 9 ).…”

Section: Introductionmentioning

confidence: 99%

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Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome

Enjezab¹,

Eftekhar²,

Ghadiri‐Anari³

2017

Electron Physician

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BackgroundPolycystic ovary syndrome (PCOS), as the most common endocrine disorder among reproductive-aged women may lead to psychological morbidity.ObjectivesThe present study set out to evaluate the severity of depression in PCOS and non-PCOS women and to evaluate correlation between depression score with body mass index, HOMA-IR, and testosterone level in every group (PCOS and non-PCOS women) in Yazd province.MethodsIn this cross-sectional study, 62 women with PCOS and 61 non- PCOS subjects (20 to 40 years) who were attending Imam-Ali Clinic in Yazd, Iran from September 2014 through March 2015 participated. These persons completed the Beck Depression Short Inventory (BDI-S) Questionnaire. Frequency of depression in PCOD and healthy persons and correlation between depression severity with body mass index, HOMA-IR, testosterone level in PCOS and non- PCOS women were evaluated by ANOVA test and independent-samples t-test and Pearson correlation. P-value of less than 0.05 was considered as statistically significant. Data analyses were performed using SPSS version 16.ResultsOf 62 PCOS subjects, 40 (64.5%) were verified positive for depression, determined by the BDI-S Questionnaire. In the control group, 60.7% had depression. Mean±SE score of depression for PCOS and non-PCOS women were 7.47±5.54 and 7.57±5.77 respectively. There was no statistically significant correlation between body mass index, HOMA-IR, testosterone level with depression score in either group separately or together.ConclusionsWe found considerable amounts of depression in our population. There is no correlation between body mass index, HOMA-IR, and testosterone level with depression score in our study.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome

Enjezab¹,

Eftekhar²,

Ghadiri‐Anari³

2017

Electron Physician

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“…Depression is defined as a type of mood illness characterized by a persistent sense of sadness and lack of interest. The study showed that women are about twice as likely as males to suffer from depression [5]. In addition to that women who started using a contraceptive patch experienced roughly twice the risk of subsequently starting an antidepressant or being diagnosed with depression [6].…”

Section: Introductionmentioning

confidence: 95%

Oral Contraceptive Use and its Association with Depression among Women in Taif, Saudi Arabia

Al-Ziyadi¹,

AlNemari²,

AlOsaimi³

et al. 2023

Int J Pharm Res Allied Sci

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The oral contraceptive pill (OCP) is a type of birth control pill that is taken orally. OCP is the world's most frequently used contraceptive method today. To estimate the prevalence of depression among hormonal contraceptive users in Taif city. The study was a cross-sectional questionnaire survey, based on a structured questionnaire that was developed by authors conducted in Taif city in the kingdom of Saudi Arabia The required sample was calculated, which is approximately 384. The prevalence of using oral contraceptive pills (OCPs) was found to be 57.5% The Beck Depression Inventory (BDI) score was calculated by adding the scores of all the items in the questionnaire. The mean scores for the BDI were found to be 14.1 ± 10.1. A BDI score of 17 or more was considered to have clinical depression, and it was found that the prevalence of depression was 37.8%. The Levels of Depression were calculated based on the total score as Normal (1-10), Mild mood disturbance (11)(12)(13)(14)(15)(16), , Extreme depression (>40). The analysis showed that 2.4% and 4.4% demonstrated extreme and severe depression, respectively. The findings showed that females' oral contraceptive pills were the most commonly used contractive methods. About 37.8% of the females who used OCPs had demonstrated depression symptoms.

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“…It can lead to a variety of psychological issues. Affected women may experience anxiety and depression (Irak et al, 2016). Hirsutism is one of the most important predictors of poor quality of life in women with PCOS (Guyatt et al, 2004;Kiran et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of anxiety and depression among hirsutism patients in Herat city

Kakar,

Ahmad Joya

2022

ARJ

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Hirsutism induces mental illnesses such as depression and anxiety, and it is important to know the prevalence of these disorders in societies. The aim of this study was to determine the prevalence of anxiety and depression in patients with hirsutism in Herat city. This cross-sectional study was conducted from August 1, 2018, to the end of July 2019 in Herat city of Afghanistan and were included 138 participants. The Ferriman-Gallwey scale for diagnosis and determining the severity of hirsutism, the Hospital Anxiety and Depression Scale (HADS) for diagnosis and severity assessment of depression and anxiety; and the IBM program SPSS Statistics for analyzing the data were used. This study has shown that anxiety (61.5%) was more prevalent than depression in study population (52.8%). Anxiety was present in (5.0%) of illiterate patients (29.7%) of school level, and (26.8%) with higher education levels. Depression was present in 5.0% of illiterate, 23.9% of patients with the school level, and 23.9% of patients with a high level of education. According finding of this study we concluded that depression and anxiety disorders are present in more than half of the patients with hirsutism in Herat city. The severity of depression and anxiety is not associated with the degree and severity of hirsutism. Anxiety was more prevalent among patients with higher education. This study builds on the current available literature on the high prevalence of mental disorders among hirsute patients and highlight the need to address this important public health issue in the community.

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Depression, anxiety, and their relation with clinical parametersand androgen levels in hirsute women

Cited by 6 publications

References 31 publications

Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome

Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome

Oral Contraceptive Use and its Association with Depression among Women in Taif, Saudi Arabia

Prevalence of anxiety and depression among hirsutism patients in Herat city

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