Background-Depression is often undiagnosed and untreated. It is not clear if differences exist in the diagnosis and treatment of depression among pregnant and nonpregnant women. We sought to estimate the prevalence of undiagnosed depression, treatment by modality, and treatment barriers by pregnancy status among U.S. reproductive-aged women.Methods-We identified 375 pregnant and 8,657 nonpregnant women 18-44 years of age who met criteria for past-year major depressive episode (MDE) from 2005-2009 nationally representative data. Chi-square statistics and adjusted prevalence ratios (aPR) were calculated.Results-MDE in pregnant women (65.9%) went undiagnosed more often than in nonpregnant women (58.6%) (aPR 1.1, 95% confidence interval [CI] 1.0-1.3). Half of depressed pregnant (49.6%) and nonpregnant (53.7%) women received treatment (aPR 1.0, 95% CI 0.90-1.1), with prescription medication the most common form for both pregnant (39.6%) and nonpregnant (47.4%) women. Treatment barriers did not differ by pregnancy status and were cost (54.8%), opposition to treatment (41.7%), and stigma (26.3%).Conclusions-Pregnant women with MDE were no more likely than nonpregnant women to be diagnosed with or treated for their depression.
IntroductionDepression is a leading cause of global disability and the second leading cause of global disease burden among people 15-44 years of age. 1 Women are disproportionately affected, as they are almost twice as likely as men to report lifetime history of major depressive episode (MDE). 2,3 Depression affects 8%-16% of U.S. reproductive-aged women 2,4-6 and © Mary Ann Liebert, Inc.
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MeasuresMajor depressive episode-MDE was assessed using nine questions about MDE symptoms, as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). 24 A respondent met DSM-IV criteria for past-year MDE if she reported experiencing ≥5 symptoms nearly every day in the same 2-week period in the past 12 months, with at least 1 of the 5 symptoms being depressed mood or loss of interest or pleasure in daily Women also self-reported whether a doctor or other medical professional had told them that they had depression in the past year, which was asked separately from MDE symptoms and is referred to hereafter as having a clinical diagnosis of depression.Mental health treatment-Three NSDUH questions assessed past-year treatment.Respondents were asked: "During the past 12 months, did you take any prescription medication that was prescribed for you to treat a mental or emotional condition? During the past 12 months, did you receive any outpatient treatment or counseling for any problem you were having with your emotions, nerves, or mental health? During the past 12 months, have you stayed overnight or longer in a hospital or other facility to receive treatment or counseling for any problem you were having with your emotions, nerves, or mental health? Mental health treatment was defined as receiving prescription medication, counseling, or inpatient care in the past year.Res...