Depression in dialysis patients: Rubidium supplementation before other drugs and encouragement?

DeCostanzi, Ester; Branciforte, L; Caropreso, A; Nonnato, Antonello; Sabbioni, E.; Canavese, Caterina

doi:10.1046/j.1523-1755.2001.0600031201.x

Cited by 8 publications

(4 citation statements)

References 3 publications

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“…Depressed patients show deficient in Rb concentration, so supplementation may be necessary for those patients [14].It is used in high PH therapy and to decrease tumor growth,muscle pain, multiple sclerosis, tetany, spasmophilia. Depletion of Rb affects minerals (zinc, copper, phosphorus, calcium, magnesium, iron, sodium and potassium) status.…”

Section: Rubidium (Rb)mentioning

confidence: 99%

Clinical Correlations Between Cesium, Cobalt, Manganese, Rubidium and Rhenium with the Pathogenesis of Rheumatoid Arthritis

Moustafa¹

2015

SJCM

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Background and Objectives: Rheumatoid arthritis is one of the most common inflammatory diseases. Studies indicated that increased oxidative stress or defective antioxidant status with inflammation contribute to the pathogenesis of disease. This study was emphasized that levels of some trace elements altered due to oxidative stress and inflammatory process which are associated with the pathogenesis of rheumatoid arthritis. This study was aimed to assess the serum levels of cesium, cobalt, manganese, rubidium and rhenium in patients group as compared with the control group and investigate the effect of other confounding factors like rheumatoid factor, age, gender and finally estimate the correlation between studied parameters. It was hypothesized that there were an alteration in levels of parameters due to oxidative stress and inflammatory process which are associated with the etiology and pathogenesis of rheumatoid arthritis. Method: This case control study conducted on 56 Iraqi patients of both genders 30 men and 26 women with the average age (40-57) years and 56 of age-gender matched apparently healthy adults were also enrolled in this study as a control group. The patients were free from any diseases except rheumatoid arthritis and this was confirmed by clinical examination and biochemical and hematological tests. Levels of parameters were estimated using atomic absorption spectrophotometers. Results: There were no significant differences between RF positive and negative groups regarding the studied parameters. There were a significant reduction in cesium and rubidium and a significant elevations in cobalt, manganese and rhenium in patients as compared with the control group. There were no significant differences between rheumatoid factor positive and negative groups regarding focused parameters in men and women groups, except for age factor in women group, there were no significant differences between different age categories in rheumatoid factor positive and negative regarding focused parameters. In addition, there was no significant correlation among studied parameters. Conclusion: Levels of parameters were significantly altered in patients group. These alterations proved the possible association with pathogenesis of rheumatoid arthritis. Therefore, the estimation of these parameters could be a useful complementary non-invasive diagnostic tool to determine trace elements status for treatment and diagnosis of disease. These variations are probably responsive to oxidative stress concomitant with inflammation induced by cytokines and resulted from defensive mechanism of patients. Inflammatory mediators affect on trace elements homeostasis in rheumatoid arthritis.

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Section: Rubidium (Rb)mentioning

confidence: 99%

Clinical Correlations Between Cesium, Cobalt, Manganese, Rubidium and Rhenium with the Pathogenesis of Rheumatoid Arthritis

Moustafa¹

2015

SJCM

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“…So, what exactly does this mean? Well, endorphins make you dream, polyphenols enlarge your coronary arteries and veins, and rubidium alleviates depression and puts a smile on your face [41] . What more could you ask for?…”

Section: The Brain's 2 Hemispheresmentioning

confidence: 99%

Rubidium, Salami and Depression

Canavese¹,

DeCostanzi²,

Bergamo³

et al. 2008

Blood Purif

Self Cite

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Background: Depression may induce malnutrition, but, as a paradoxical hypothesis, malnutrition may induce depression. This relationship, of course, depends on how we define malnutrition. Current Knowledge: Rubidium is a trace element strongly linked with depression, and is deficient in uremia sufferers. However, in uremic patients, rubidium deficiency is more evident during predialysis, as it is at least partially corrected during dialysis and after transplantation. It seems that diet restrictions might be the main cause of rubidium deficiency, as it is mainly found in red meat. Conclusion: If rubidium is found in salami, then the occasional slice could be more beneficial for people suffering from depression than taking a lot of medication.

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“…1.9.27 Rubidium. Following concerns over imbalances of trace elements in dialysis patients, Canavese et al 194 used both ETAAS and NAA to study Rb levels in uraemic patients. Serum concentration of Rb were quantitatively determined in a group of patients undergoing chronic haemodialysis (HD) by ETAAS, whilst NAA was used to quantitatively determine Rb levels in biopsy or autopsy samples from 20 HD patients.…”

Section: Marine and Freshwater Biologymentioning

confidence: 99%

Atomic spectrometry update. Clinical and biological materials, foods and beverages

Taylor

Branch²,

Halls

et al. 2002

J. Anal. At. Spectrom.

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Depression in dialysis patients: Rubidium supplementation before other drugs and encouragement?

Abstract: LETTER TO THE EDITOR concentration when nephrologists face uremic depres-Depression in dialysis sion? If rubidium deficiency is confirmed, it might allow supplementation, which could add to the tools for the patients: Rubidium war against uremic depression.

Cited by 8 publications

References 3 publications

Clinical Correlations Between Cesium, Cobalt, Manganese, Rubidium and Rhenium with the Pathogenesis of Rheumatoid Arthritis

Clinical Correlations Between Cesium, Cobalt, Manganese, Rubidium and Rhenium with the Pathogenesis of Rheumatoid Arthritis

Rubidium, Salami and Depression

Atomic spectrometry update. Clinical and biological materials, foods and beverages

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