“…20,48,65e68 There is intrinsic difficulty in assessing depressive symptoms in individuals whose advanced life-limiting illnesses might mimic depressive symptoms, as well as challenges in providing interventions likely to be effective in time. 1,26 Further barriers to suboptimal recognition, assessment and management include: clinicians' fear of distressing patients, especially given the stigma associated with psychiatric diagnoses; 3,69 lack of awareness and skills to detect and manage depression; 20,68,70e75 perceived lack of resources such as time, 20,68,76 acceptable assessment tools and access to mental health services; 20,69,77e82 beliefs that depression is ''normal''; 69,76 and that screening and interventions are likely to be futile in this context. 70,71,73,83 It is possible that addressing these barriers might lead to an earlier detection and management of depressive symptoms in people with advanced life-limiting illnesses.…”